Physical Activity may help delay cognitive decline by modulating neurodegeneration and AD-specific tau pathologies: a study reveals
Alzheimer disease (AD), the most common cause of cognitive impairment, is characterized by β-amyloid (Aβ) plaques and tau neurofibrillary tangles, which lead to neuroinflammation, neurodegeneration, and cognitive decline. Among various interventions, physical activity (PA) is widely recommended. Numerous studies suggest that PA not only slows cognitive decline but also improves specific cognitive functions. Potential mechanisms underlying the protective