At a Glance Calorie restriction for two years led to weight loss and a substantial reduction in risk factors for heart disease and diabetes in healthy adults 50 or younger. The findings suggest that a sustained restriction of caloric intake may reduce the risk for heart disease and diabetes. Calorie restriction is a type of
Using the tendency of circulating cancer cells to adhere to carbon nanotubes, the easily mass-produced chip captures living cells and cell clusters of multiple types and sizes with high reliability and makes them available for analysis. The chip could be used to detect tumors at the earliest stages, before they can metastasize Researchers at Worcester
Source STAT Okay, the “sewing machine” is pretty cool. But if the device that Elon Musk’s neurotechnology startup Neuralink developed to implant thousands of electrodes into brains (of rats and monkeys so far, and humans eventually) were its only accomplishment, Tuesday night’s big reveal would have been a big meh. Instead, six independent experts in the kind
Source https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(19)30171-6 Mitochondria display a dynamic and heterogeneous phenotype that facilitates the metabolic heterogeneity and plasticity of cancer cells. The altered metabolic functions and dynamics of mitochondria in cancer cells, as well as mitochondrial evasion of apoptosis, provide targets for novel cancer therapeutics. The mitochondrial network has distinct morphological features that appear to be interrelated
— No price can be suggested as a fair value-based price for eteplirsen or golodirsen because no persuasive evidence yet exists to demonstrate the clinical effectiveness of either drug — — For deflazacort, discounts of at least 73% from its list price would be needed to achieve commonly cited thresholds for cost-effectiveness — — As
More than half of new drugs entering the German healthcare system have not been shown to add benefit, argue researchers. More than half of new drugs entering the German healthcare system have not been shown to add benefit, argue researchers in The BMJ today. Beate Wieseler and colleagues at the German health technology assessment agency IQWiG (Institute
Source STAT If nutritious meals can provide the same kind of benefit as medication, then why don’t health plans cover the cost of medically tailored meals, just as they cover prescription medications? It’s a question my colleagues and I at Community Servings, a nonprofit organization that provides nutritious meals for people with critical illnesses who are
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) discovered in laboratory studies that an experimental drug called selinexor may block a crucial survival pathway exploited by myelofibrosis cells. Their study was published in Clinical Cancer Research, a journal of the American Association of Cancer Research. Based on these findings, they
Extensive use of smartphones and electronic devices might be changing our bone structure. New research from the University of Queensland suggests that young people are developing a bone spur on the back of their skulls, caused by the increased prevalence of looking down. To hold our heads up, we mainly use muscles located in the spine,
Stevens calls for ‘fair prices’ from companies NHS England’s chief executive Simon Stevens was in Manchester this week at the NHS Confederation conference, delivering his latest vision of what lies ahead for the health service. Among his many announcements, he told NHS managers that patient services would have to continue to evolve, and sent a
