New research from Queen Mary University of London, published in iScience, shows an increased risk of blood clots in women who have any combination of a particular gene mutation, oestrogen use, or common medical conditions – specifically: obesity, high blood pressure, high cholesterol, and kidney disease. Women with the Factor V Leiden (FVL) gene mutation who
Key Takeaways Researchers who previously developed the first 3D human cell culture models of Alzheimer’s disease (AD) that displays two major hallmarks of the condition—the generation of amyloid beta deposits followed by tau tangles—have now used their model to investigate whether the exercise-induced muscle hormone irisin affects amyloid beta pathology. As reported in the journal Neuron,
The new International Osteoporosis Foundation (IOF) platform provides easy-to-follow exercise guidance and nutritional tips to benefit bone health, alerts to falls safety hazards in the home, and provides helpful information for caregivers. The International Osteoporosis Foundation (IOF) has launched the Build Better Bones platform, a new online resource that provides people with osteoporosis, and their caregivers, with
Genicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduce pain, especially for adults who are 50 and older, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Phoenix, March 4–9. This is the first time a
What New research offers clues about the biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. A team of researchers supported by the National Institutes of Health found evidence linking motor neurons’ large cell size and supporting structure with the genes that underlie their vulnerability
The U.S. Food and Drug Administration approved Jesduvroq tablets (daprodustat) as the first oral treatment for anemia (decreased number of red blood cells) caused by chronic kidney disease for adults who have been receiving dialysis for at least four months. Jesduvroq is not approved for patients who are not on dialysis. Other FDA-approved treatments for
NIH findings may provide early clues about increased risks for advanced biological aging and premature death. Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine(link
Study led by University Hospitals and Case Western Reserve University team details a small-molecule drug that lowers cholesterol by 70% in animal models –After statins, the next leading class of medications for managing cholesterol are PCSK9 inhibitors. These highly effective agents help the body pull excess cholesterol from the blood, but unlike statins, which are
Oxford Research reveals high blood glucose reprograms the metabolism of pancreatic beta-cells in diabetes. In diabetes, the pancreatic beta-cells do not release enough of the hormone insulin, which lowers blood glucose levels. This is because a glucose metabolite damages pancreatic beta-cell function. An estimated 415 million people globally are living with diabetes. With nearly 5
Researchers at the Technion have developed a technology to measure the long-term effect of antibiotic combinations (cocktails). These combinations are of concern to the scientific and medical community due to the fact that the use of single antibiotics often leads to the rapid development of bacterial resistance to antibiotics. The research published in Nature was led by Technion
