Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) discovered in laboratory studies that an experimental drug called selinexor may block a crucial survival pathway exploited by myelofibrosis cells. Their study was published in Clinical Cancer Research, a journal of the American Association of Cancer Research. Based on these findings, they
Extensive use of smartphones and electronic devices might be changing our bone structure. New research from the University of Queensland suggests that young people are developing a bone spur on the back of their skulls, caused by the increased prevalence of looking down. To hold our heads up, we mainly use muscles located in the spine,
Stevens calls for ‘fair prices’ from companies NHS England’s chief executive Simon Stevens was in Manchester this week at the NHS Confederation conference, delivering his latest vision of what lies ahead for the health service. Among his many announcements, he told NHS managers that patient services would have to continue to evolve, and sent a
Novel materials made with FDA-approved components could deliver large payloads of active ingredients. MIT chemical engineers have devised a new way to create very tiny droplets of one liquid suspended within another liquid, known as nanoemulsions. Such emulsions are similar to the mixture that forms when you shake an oil-and-vinegar salad dressing, but with much
As part of the Human Cell Atlas initiative, a collaborative community working to create reference maps of every human cell, researchers studied over 36,000 individual cells from the nasal area and three separate areas of the lung in samples taken from 17 people without asthma. Using single-cell transcriptomics, cell types were identified and located, and any
Source Nature Detailed analysis of misconduct investigations into huge research fraud suggests institutional probes aren’t rigorous enough. By day, Andrew Grey studies bone health. But over the past few years, he’s developed another speciality: the case of one of science’s most prolific fraudsters. From 1996 to 2013, Yoshihiro Sato, a Japanese bone-health researcher plagiarized work,
Research supported by the Accelerating Medicines Partnership (AMP) on Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) provides new insights into tissue damage for these autoimmune conditions. Findings include the identification of novel molecular signatures related to immune system signaling in kidney cells that may reflect their active role in disease process; molecular targets, including specific white blood
Nutrigenomics — the nexus of nutrition, genetics and genomics — is still in its infancy, but USC researcher Cary Kreutzer sees vast potential in its ability to help people take control of their health. ne day, you may walk into your doctor’s office and come out with a diet that’s been personalized for your unique
The U.S. Food and Drug Administration today approved Emgality (galcanezumab-gnlm) solution for injection for the treatment of episodic cluster headache in adults. “Emgality provides patients with the first FDA-approved drug that reduces the frequency of attacks of episodic cluster headache, an extremely painful and often debilitating condition,” said Eric Bastings, M.D., deputy director of the
Michigan State University physicians have found that vitamin D, if taken for at least three years, could help cancer patients live longer. The findings suggest that the vitamin carries significant benefits other than just contributing to healthy bones and were presented at the American Society of Clinical Oncology annual meeting on June 3, 2019. In
