A team led by Scripps Research scientists has uncovered key details of an immune-cell process that frequently underlies excessive inflammation in the body. The findings could lead to new ways of preventing and/or treating inflammation-related conditions such as sepsis, arthritis, and coronary artery disease. In the study, published September 21, 2022 in Nature Communications, the researchers
The World Health Organization says Ghana has reported two possible cases of the Ebola-like Marburg virus disease, which if confirmed would mark the first-ever such infections in the West African country. The disease, a very infectious hemorrhagic fever in the same family as Ebola, is spread to people by fruit bats and transmitted among people through direct
Understanding how a type of white blood cell called a neutrophil behaves at the site of a tissue injury might one day lead to advances in wound repair and inflammation, said Dr. Anna Huttenlocher, at the first in-person NIH Director’s Wednesday Afternoon Lecture in Lipsett Amphitheater since March 2020. Known as the immune system’s first
Recently, there have been reports of children with a severe acute form of hepatitis in the UK, Europe, the USA, Israel, and Japan. Most patients present with gastrointestinal symptoms and then progress to jaundice and, in some cases, acute liver failure. So far, no common environmental exposures have been found, and an infectious agent remains
Researchers from the Medway School of Pharmacy (a partnership between the universities of Kent and Greenwich) have helped isolate the Lloviu virus (LLOV) – a close relative of Ebola virus – for the first time, highlighting the need for future research to ensure pandemic preparedness. LLOV is part of the filovirus family – which includes the Ebola
The pig heart transplanted into an American patient earlier this year in a landmark operation carried a porcine virus that may have derailed the experiment and contributed to his death two months later, say transplant specialists. David Bennett Sr. was near death in January when he received a genetically edited pig heart in a pioneering between-species transplant
During October–November 2021, clinicians at a children’s hospital in Alabama identified five pediatric patients with severe hepatitis and adenovirus viremia upon admission. In November 2021, hospital clinicians, the Alabama Department of Public Health, the Jefferson County Department of Health, and CDC began an investigation. This activity was reviewed by CDC and conducted consistent with applicable
Taking drugs to fight nausea and vomiting can increase the risk of ischemic stroke, according to a new study from Inserm. Increased risks from the first days of treatment. Anti Dopaminergic Antiemetics are associated with an increased risk of developing a stroke . It was researchers from Inserm and the University of Bordeaux who highlighted this link. The results have been
A human immune system is a lot like the board game Mouse Trap: it’s a Rube Goldberg system of interacting parts. Only instead of a falling ball causing a tiny diver to leap into a tub—which, in turn, springs a trap on some plastic mice—proteins trigger other proteins to activate immune cells and direct them
Fusion surgery has been the long-standing treatment for people with scoliosis – a side-to-side curve of the spine. But other options have become available — including vertebral body tethering for children with scoliosis. “Vertebral tethering is a new tool in the tool kit for the treatment of scoliosis,” says A. Noelle Larson, M.D., a pediatric orthopedic surgeon at Mayo
