University of Florida researchers identify safer pathway for pain relief

University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional pain medications. In a new study published in Nature Communications, researchers describe how this drug compound provides pain relief without the dangerous side effects commonly associated with opioids administered to

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Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques

A new study published in Nature Cardiovascular Research found that while carotid artery narrowing can lead to stroke in both men and women, the symptoms and plaque characteristics often differ between the sexes. Even though the main types of cells in the plaques are similar, important differences exist in the smaller structures within those cells. According to the World

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Stephen Hauser and Andrea Ascherio Win Breakthrough Prize in Life Sciences for Role in Redefining MS

Stephen hauser and Andrea Ascherio have played a pivotal part in identifying the cause of multiple sclerosis, leading to a new generation of game-changing therapies. Neuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences. Hauser, a UCSF professor of

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Major advances in the treatment of type 1 diabetes

Recent decades have seen a lot of progress in diabetes treatment. In a new study, Per-Ola Carlsson, Professor of Medical Cell Biology, has obtained promising results. “This is the first time anyone has succeeded in transplanting insulin-producing cells into another individual without immunosuppressive drugs,” he says. The treatment available for type 1 diabetes since the

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Blood test can predict dementia risk up to 10 years in advance, study shows

Researchers at Karolinska Institutet have shown how some specific biomarkers in the blood of cognitively healthy elderly people can predict the development of dementia up to ten years before diagnosis. A new study published in Nature Medicine has examined the ability of specific biomarkers to predict dementia, including Alzheimer’s disease, in cognitively healthy older adults up to

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FDA Approves Tenecteplase for Acute Ischemic Stroke

Key Takeaways The FDA has approved tenecteplase (TNKase; Genentech) for the treatment of acute ischemic stroke (AIS) in adults, according to a Genentech announcement.1 The thrombolytic medicine is an intravenous (IV) tissue plasminogen activator that is clot-dissolving, administered as a single 5-second IV bolus. The company noted that it will be providing a 25-mg vial configuration

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Magnetic microrobots remove blood clot from sheep’s femoral artery

Researchers from the University of Twente’s TechMed Centre and Radboud University Medical Centre removed blood clots using wireless magnetic robots. This innovation could revolutionise the treatment of life-threatening vascular diseases such as thrombosis. Cardiovascular diseases such as thrombosis are a major health problem worldwide. Worldwide, one in four people die each year from conditions caused

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New blood test could improve Alzheimer’s Disease diagnosis, research finds

Up to half of all people living with Alzheimer’s Disease in Ireland remain undiagnosed. A new blood test may have the potential to transform patient care, allowing for better diagnosis, earlier interventions and more targeted treatments Researchers at Trinity College, the Tallaght Institute of Memory and Cognition and St James’s Hospital, Dublin are exploring the

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