Category REGENERATIVE MEDICINE

PIER MARIA FORNASARI
2019-03-12

The human reference genome falls short in ways that have become embarrassing, misleading, and emblematic of the white European dominance of science.

Here’s why that’s undermining personalized medicine In a paper published last week, scientists led by Dr. Pui-Yan Kwok of the University of California, San Francisco, analyzed 154 genomes from 26 ethnic populations, from Han Chinese and Tuscans to Yoruba, Esan, Puerto Ricans, and Peruvians. They found 60 million bases in one or more of these populations

Read More

No Comments InGENOME
PIER MARIA FORNASARI
2019-03-11

Smart Needle

Researchers invent a resistance-sensing injection device that knows where to go Syringes and hollow needles—among the most feared and most commonly used tools in medical practice—have been around for more than a century.  However, the precise insertion of these devices depends largely on the technique and skill of the person delivering the injection. And some anatomical

Read More

7 comments InREGENERATIVE MEDICINE
PIER MARIA FORNASARI
2019-03-11

New Insight into Aging Hearts

Molecular pathway plays major role in the intersection between aging and heart failure A team led by Harvard Medical School researchers based at Massachusetts General Hospital has found that activity of an important signaling pathway increases with aging and with heart failure. In a report published in Science Translational Medicine, the team describes evidence from both humans

Read More

No Comments InAGEING
PIER MARIA FORNASARI
2019-03-07

Scientists find method to boost CRISPR efficiency

Discovery made while editing genetic defect behind Duchenne muscular dystrophy Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases. The finding stemmed from research at UT Southwestern in which a single-cut gene-editing

Read More

7 comments InGENE THERAPY RARE DISEASES
PIER MARIA FORNASARI
2019-03-07

Real Microgravity Promotes Myocardial Differentiation of Induced Pluripotent Stem Cells: Results from Tianzhou-1 Space Mission

Researchers used time-lapse imaging to show that mouse induced pluripotent stem cells (iPSCs) grown during spaceflight differentiated into cardiomyocytes significantly faster than similar cells grown at Earth’s gravity. The robust cardiomyocyte formation at microgravity, which lasted for 10 days, is described in an article published in Stem Cells and Development, a peer-reviewed journal from Mary Ann Liebert,

Read More

4 comments InREGENERATIVE MEDICINE
PIER MARIA FORNASARI
2019-03-06

Scaffold-free cell patches possible with simple protocol for engineered adipose-derived stem cells

Cell sheets have previously shown greater efficacy for tissue repair than injections of single stem cells. New research conducted by scientists at the Los Angeles Biomedical Research Institute and Emmaus Life Sciences, Inc. (both CA, USA) has demonstrated the possibility of producing scaffold-free engineered cell sheets. These cell ‘patches’ could enable better organ repair follow

Read More

6 comments InREGENERATIVE MEDICINE
PIER MARIA FORNASARI
2019-03-01

The Magneuron project: remote-controlling cells to cure neurodegenerative diseases

01 MARCH 2019 P.M.Fornasari On average, people are living longer than ever before, and that’s good news. However, ageing populations mean higher rates of certain illnesses, such as neurodegenerative disorders. A prominent example of is Parkinson’s disease, a medical condition that already affects 6.5 million people worldwide. This number is expected to more than double

Read More

No Comments InCELL THERAPY
PIER MARIA FORNASARI
2019-03-01

The Alliance for Regenerative Medicine Publishes First-Ever Rare Disease Report, Detailing Financial & Clinical Progress of 323 Rare-Disease Focused Cell & Gene Therapy Developers Worldwide

01 March 2019 P.M.Fornasari Rare diseases affect fewer than roughly five in 10,000 people worldwide. Approximately 80% of rare diseases have identified genetic origins, and are often debilitating; about 30% of children with a rare disease will die before their fifth birthday. There are roughly 30 million people in the U.S. living with a rare

Read More

One comment InGENE THERAPY RARE DISEASES