Old human cells can become more youthful by coaxing them to briefly express proteins used to make induced pluripotent cells, Stanford researchers and their colleagues have found. The finding may have implications for aging research. Old human cells return to a more youthful and vigorous state after being induced to briefly express a panel of
Team combining AI, bioelectronics, regenerative medicine to regrow muscle tissue Rice University neuroengineers and bioengineers are part of a national team that’s developing “smart” technology that combines artificial intelligence, bioelectronics and regenerative medicine to regrow muscle tissue for wounded soldiers. Rice neuroengineers and bioengineers are part of a national team that’s developing REPAIR, an electronic
New research has found that there are 362 cell and gene therapies in clinical pipelines in the US, an increase from 2018. A new report from America’s Biopharmaceutical Companies has revealed that there are 362 cell and gene therapies in development in the US. Roughly a third of the therapies, 132, are potential treatments for rare diseases. The research
A population of stem cells with the ability to generate new bone has been newly discovered by a group of researchers at the UConn School of Dental Medicine. In the journal STEM CELLS, lead investigator Dr. Ivo Kalajzic, professor of reconstructive sciences, postdoctoral fellows Dr. Sierra Root and Dr. Natalie Wee, and collaborators at Harvard, Maine
A person with a genetic condition that causes blindness has become the first to receive a CRISPR–Cas9 gene therapy administered directly into their body. The treatment is part of a landmark clinical trial to test the ability of CRISPR–Cas9 gene-editing techniques to remove mutations that cause a rare condition called Leber’s congenital amaurosis 10 (LCA10).
ARM today released its 2019 Annual Report and Sector Year in Review, highlighting the organization’s key priorities and initiatives, as well as offering an in-depth look at trends and metrics for the cell therapy, gene therapy, and tissue engineering sector. ARM, which celebrated its 10th anniversary in 2019, is the premier international advocacy organization representing the cell
The Canadian government is investing almost $7 million in stem cell research and regenerative medicine. William Amos, Parliamentary Secretary to the Minister of innovation, Science and Industry, was at Maisonneuve-Rosemont Hospital Monday to announce that $6.9 million would go to the Stem Cell Network’s competitive research funding program. “Stem cell and regenerative medicine are a
Researchers use lipids to safely deliver gene therapy to the eye, successfully holding off advance of rare, inherited eye disorder Researchers at Case Western Reserve University have used a unique method to safely deliver gene therapy to fight a rare, but irreversible, genetic eye disorder known as Stargardt disease. By using chemically modified lipids—instead of the
Gene therapy to treat Huntington’s disease Huntington’s disease (HD) is a rare disease characterized by abnormal chorea movement and caused by Huntingtin (Htt) gene mutation and neurodegeneration in a brain area called striatum. A research group led by Dr. Gong Chen, a former professor at Penn State University and now leading a brain repair center
The excitement about cell and gene therapies is almost tangible within the biotech and pharma industry. Over 950 companies are actively developing advanced therapies, which are expected to make exceptional improvements to peoples’ lives in the next decade. Although hopes are high, the industry still faces a number of challenges in cell and gene therapy manufacturing, mainly
