Category REGENERATIVE MEDICINE

PIER MARIA FORNASARI
2022-05-31

Recent progress in cell therapy research: a review in Nature outlines engineering disciplines, genome and epigenome editing, synthetic biology and biomaterial-mediated immune modulation.

Given recent progress in cell therapy research, it is clear that the engineering disciplines outlined in this Review will play an increasing role in the creation of new product pipelines with improved safety, efficacy and accessibility for patients. Recent scientific advances have not only demonstrated the potential impact of technologiesdeveloped by each of these fields,

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No Comments InADVANCED THERAPY MEDICINAL PRODUCT REGENERATIVE MEDICINE
PIER MARIA FORNASARI
2022-05-21

‘Cell pores’ discovery and a new drug give hope to millions of brain and spinal cord injury patients

Scientists from the University of Birmingham have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal cord. Their research, published today in Clinical and Translational Medicine, demonstrates that AZD1236, a drug developed by AstraZeneca, can significantly reduce “secondary damage” caused by the body’s response to spinal

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No Comments InBRAIN
PIER MARIA FORNASARI
2022-05-14

New type of cell therapy can repair damaged heart tissue after infarction

Researchers at Karolinska Institutet, Technical University of Munich (TUM) in Germany and AstraZeneca, among others, have identified a new type of cell therapy with the potential to heal injuries to the heart after a heart attack. The preclinical study, published in the journal Nature Cell Biology, shows that so-called ventricular progenitor cells can stimulate the heart’s

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No Comments InCELL THERAPY
PIER MARIA FORNASARI
2022-05-12

Novel Supramolecular CRISPR–Cas9 Carrier Enables More Efficient Genome Editing

Fifth generation polyrotaxane (PRX) carriers can effectively deliver CRISPR-Cas9 ribonucleoproteins (RNPs) The PRX carrier can cross the cell membrane, avoid endosomal action, and release Cas9 RNP for entry into the nucleusImage courtesy: Kumamoto University, The carriers, aminated polyrotaxanes, can flexibly and reversibly bind with Cas9 ribonucleoprotein and protect it from intracellular endosomal degradation CRISPR-Cas9 is

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No Comments InCRISPR
PIER MARIA FORNASARI
2022-04-29

Financial risks posed by unproven cell interventions in Japan

The research group led by Professor Misao Fujita conducted a study to estimate the total amount of refund the Japanese government would pay if a patient received unproven cell interventions and applied for a medical expense deduction. Some regenerative medicines whose safety and efficacy have not been fully confirmed in clinical trials and other studies are offered

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No Comments InADVANCED THERAPY MEDICINAL PRODUCT REGENERATIVE MEDICINE
PIER MARIA FORNASARI
2022-04-20

Regenerative Potential of Solid Bone Marrow Aspirate Concentrate Compared to Platelet-Rich Fibrin

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A. Blood concentrate material such as platelet-rick fibrin (PRF) is used in clinical practice to promote tissue regeneration in the

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No Comments InREGENERATIVE MEDICINE