This report includes an overview of regenerative medicine approaches to treating a variety of cancer types, along with a list of ARM member companies active in developing these therapies, global financings, an overview of the oncology-focused clinical pipeline, as well as commentary from select therapeutic developers active in this area. Key findings include: There are 416 companies worldwide active in

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Reviews Gene Editing for Immune Cell Therapies Autologous T cells that have been genetically modified to express a chimeric antigen receptor targeting the B cell antigen CD19 have yielded remarkable clinical responses in patients with B cell malignancies, and are now on the market as anticancer ‘drugs’. [Nat Biotechnol] Abstract The Next Generation of CRISPR-Cas Technologies

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Dr. Robert A. Preti, theCEO and President of Hitachi Chemical Advanced Therapeutics Solutions (HCATS), was recently interviewed by Global Business Reports (GBR) for their 2019 US Biopharmaceuticals report. The GBR report covers a range of topics, such as the state of the biopharma industry, new developments in biopharmaceutical manufacturing, the investment climate for cell and gene

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Athersys announced additional favorable data from its exploratory Phase 1/2 acute respiratory distress syndrome (ARDS) clinical trial. Dr. Geoff Bellingan, Medical Director at University College London Hospitals, described the data from the clinical trial, referred to as the MUST-ARDS trial, during his presentation today at the American Thoracic Society International Conference in Dallas, Texas, the

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While therapies that harness the power of the immune system against cancer have made remarkable progress against certain types of tumours, they still remain ineffective in most cancer patients. A new study has described a method of reprogramming the regulatory T cells that usually suppress immune responses into inflammatory cells that not only permit but

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01 MARCH 2019 P.M.Fornasari On average, people are living longer than ever before, and that’s good news. However, ageing populations mean higher rates of certain illnesses, such as neurodegenerative disorders. A prominent example of is Parkinson’s disease, a medical condition that already affects 6.5 million people worldwide. This number is expected to more than double

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