Category Covid-19

PIER MARIA FORNASARI
2020-04-07

Analysis of Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

In a paper just published on JAMA is reported a retrospective case series that involved 1591 critically ill patients admitted from February 20 to March 18, 2020. 99% (1287 of 1300 patients) required respiratory support, including endotracheal intubation in 88% and noninvasive ventilation in 11%; ICU mortality was 26%. Retrospective case series were referred for

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PIER MARIA FORNASARI
2020-04-07

Chinese scientists seeking potential COVID-19 treatment find ‘effective’ antibodies in convalescent plasma

A team of Chinese scientists has isolated several antibodies that it says are “extremely effective” at blocking the ability of the new coronavirus to enter cells, which eventually could be helpful in treating or preventing COVID-19. There is currently no proven effective treatment for the disease, which originated in China and is spreading across the

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PIER MARIA FORNASARI
2020-04-07

ICNARC (intensive care national audit and research center) Report on 2249 patients critically ill with COVID-19

This report contains data on all confirmed COVID-19 cases reported to ICNARC up to midday on 03 April 2020 from critical care units participating in the Case Mix Programme (all NHS adult, general intensive care and combined intensive care/high dependency units inEngland, Wales and Northern Ireland, plus some specialist and non-NHS critical care units). Reporting

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PIER MARIA FORNASARI
2020-04-07

NICE advises against using NSAIDs for fever in patients with suspected cases of Covid-19

Paracetamol should be used in preference to non-steroidal anti-inflammatory drugs for managing fever in patients with suspected covid-19 until more evidence is available on the safety of NSAIDs, the National Institute for Health and Care Excellence advises in a rapid guideline on managing symptoms of covid-19 in the community.1 Patients with cough symptoms should take

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PIER MARIA FORNASARI
2020-04-06

FDA clears investigational new drug application for Mesoblast to use Remestemcel-L in patients with acute respiratory distress syndrome caused by COVID-19 under compassionate use and in a planned randomized controlled trial.

Mesoblast Limited today announced that it has received clearance from the United States Food and Drug Administration (FDA) for an Investigational New Drug (IND) application to treat patients with acute respiratory distress syndrome (ARDS) caused by coronavirus infection (COVID-19) with intravenous infusions of its allogeneic mesenchymal stem cell (MSC) product candidate Remestemcel-L. Mesoblast Chief Medical

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PIER MARIA FORNASARI
2020-04-03

A new study by The Scripps Research Institute and Hong Kong University determined the crystal structure of CR3022, a neutralizing antibody previously isolated from a convalescent SARS patient

The outbreak of COVID-19 caused by SARS-CoV-2 virus has now become a pandemic, but there is currently very little understanding of the antigenicity of the virus. Source Science A recent study has shown that CR3022 can also bind to the RBD of SARS-CoV-2 . This finding provides an opportunity to uncover a cross-reactive epitope. Therefore

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