China’s COVID-19 wave forecast to have two peaks where cases could reach 4.2 million a day: ew modelling by Airfinity examining data from China’s regional provinces

China is predicted to see two peaks in cases as COVID-19 spreads throughout the country, the first peak in mid-January and the second in early March.  New modelling by Airfinity has examined data from China’s regional provinces. The current outbreak is growing more rapidly in some regions than in others. Cases are currently rising much

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Global study presents first results on the longer-term effects of therapies for the treatment of critically ill patients with COVID-19

The world’s largest trial into the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes has released results from the 180-day (six month) follow-up of 4869 critically ill patients. Published today in The Journal of the American Medical Association (JAMA), the study is part of the ongoing Randomized Embedded Multifactorial Adaptive Platform

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Efficacy and safety of COVID‐19 vaccines: a Cochrane Systematic Review

A comprehensive review of all the evidence available from randomized controlled trials of COVID 19 vaccines up to November 2021 has concluded that most protect against infection and severe or critical illness caused by the virus. The review, performed by a collaboration of independent, international experts, and published in Cochrane Library also found there was

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The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid 2 phosphorylation and inhibits viral infection in vitro

A cross-institutional effort between researchers at Weill Cornell Medicine and Duke University has yielded exciting progress in the search for new therapeutics against Covid-19. Where much of our current anti-SARS-CoV-2 arsenal is built around the virus’ spike (S) protein, many other proteins contribute to the viral life cycle as well. This includes the nucleocapsid (N) protein, which

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Researchers discover dysregulation of the immune system mediated by ATP as a new mechanism associated with severe COVID-19.

Researchers at the University of São Paulo (USP) in Brazil have found that severe COVID-19 is associated with an imbalance in an important immune system signaling pathway. The discovery helps explain at the molecular level why some people infected by SARS-CoV-2 develop a potentially fatal systemic inflammation. It also paves the way to the development

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