Category Covid-19

PIER MARIA FORNASARI
2021-02-08

ORF9b from SARS-CoV-2, upon viral infection, antagonizes IFN-β and pro-inflammatory cytokines production mediating its interaction with NEMO and interrupting the K63-linked polyubiquitination of NEMO.

COVID-19 is a current global health threat caused by the novel coronavirus SARS-CoV-2. Emerging evidence indicates that SARS-CoV-2 elicits a dysregulated immune response and a delayed interferons (IFNs) expression in patients, which contribute largely to the viral pathogenesis and development of COVID-19. However, underlying mechanisms remain to be elucidated. In this paper, it’s reported the

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PIER MARIA FORNASARI
2021-02-07

A two-dose regimen of the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccine provides minimal protection against mild-moderate COVID-19 infection from the B.1.351 coronavirus variant.

The Johannesburg Witwatersrand University Vaccines and Infectious Diseases Analytics (VIDA) Research Unit, which runs the Oxford Covid-19 vaccine trial in South Africa, has announced results. In an analysis, submitted as a pre-print prior to peer-review publication, a two-dose regimen of the ChAdOx1 nCoV-19 vaccine provides minimal protection against mild-moderate COVID-19 infection from the B.1.351 coronavirus

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PIER MARIA FORNASARI
2021-02-07

A new study confirms the CDC prediction that B.1.1.7 UK variant will dominate US Covid-19 cases by March.

A more contagious variant of the coronavirus first found in Britain is spreading rapidly in the United States, doubling roughly every 10 days, according to a new study. Analyzing half a million coronavirus tests and hundreds of genomes, a team of researchers predicted that in a month this variant could become predominant in the United States,

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PIER MARIA FORNASARI
2021-02-07

Open letter: Support data sharing for COVID-19 in European COVID-19 Data Portal

We need open data, especially open SARS-CoV-2 sequence data, and open science to beat COVID-19 and to prepare for future outbreaks. Why open data is so important When responding to a health crisis, data play a critical role in understanding transmission, infection and symptoms, and in identifying drug targets, developing vaccines and designing public health

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PIER MARIA FORNASARI
2021-02-07

A not peer reviewed paper by London School of Hygiene finds a 35% increase of dying risk linked to the B.1.1.7 COVID-19 UK variant.

Since B.1.1.7 was first identified in September in southern England, it has become the dominant variant in the United Kingdom and has spread to more than 30 countries. To investigate whether the lineage causes an increased risk of dying, Nicholas Davies, an epidemiologist at the LSHTM, and colleagues analysed data from more than 850,000 people

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