Antibodies bite worse on new omicron BA.2.75.2 variant: a study from the Karolinska Institutet shows.

A study from the Karolinska Institutet shows that the coronavirus variant BA.2.75.2, a subvariant of omicron, more easily bypasses neutralizing antibodies in the blood and is resistant to several monoclonal antibody treatments. This means an increased risk of sars-cov-2 infection this winter, unless the new updated bivalent vaccines can strengthen the immunity of the population. The results

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SARS-CoV-2 Infects Neurons and Induces Inflammation in the Brains of Rhesus Macaques

SARS-CoV-2, the COVID-19 virus, caused significant neuron damage and inflammation within a week of infection in rhesus macaque monkeys, according to a new study. The researchers from the California National Primate Research Center at the University of California, Davis, also discovered that aged monkeys with Type 2 diabetes experienced worse virus-induced neurological damage. The findings,

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SARS-CoV-2 origin: the evidence towards zoonosis is overwhelming: experts panel conclusions in PNAS. One Health approach is necessary to diminish zoonosis threats.

“Smart surveillance” for viral spillover from animals to humans, targeted preparedness and drug and vaccine research, and worldwide cooperation on surveillance and stopping disease spread are required to reduce deaths and lessen the economic consequences of the next pandemic, according to an international team of scientists. In a perspective article published this week in Proceedings of

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XBB, SARS CoV-2 variant detected in Singapore and Hong Kong, is significantly more immune evasive than BA.2.75.2 and BQ.1.1 

A fantastic diagram by Daniele Focosi showing the convergent evolution that has led to the lineages we have been discussing recently, including BQ.1.1, CA.1, BR.2 and the new XBB variant. The speed with which SARS-CoV-2 is now evolving is quite breathtaking – ever-fitter variants are now being uncovered on an almost daily basis. Just over one week

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A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets: a Cleveland Clinic study finds.

A Cleveland Clinic-led research team used artificial intelligence to map out hundreds of ways that the virus that causes COVID-19 interacts with infected cells. Through this analysis, they identified potential COVID-19 medicines within thousands of drugs already approved by the FDA for other treatments. The research focused on host-targeting therapies, which operate differently from other

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Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021

Women and people who needed to be hospitalized with Covid are much more likely to develop long Covid, according to a new peer reviewed study published in JAMA on Monday, offering new insight into the persistent and sometimes disabling condition as researchers push to develop new treatments and cures. KEY FACTS An estimated 6% of people with symptomatic Covid infections develop

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Study Provides Further Evidence That Immune Cell Dysregulation is a Driver of COVID-19 Severity

Maintenance of reparative lung macrophages may be a viable therapeutic strategy for the treatment of SARS-CoV-2 and other inflammatory lung diseases In one of the largest single-center COVID-19 cohort studies to date, researchers at the Icahn School of Medicine at Mount Sinai, using samples collected during the peak of the pandemic in New York City,

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