Category Covid-19

PIER MARIA FORNASARI
2024-11-10

COVID-19 Linked to Long-Term Risk for Autoimmune, Autoinflammatory Disease

Long-term monitoring and management of patients is crucial after COVID-19, considering demographic factors, disease severity, and vaccination status, to mitigate these risks. In a population-based study published in JAMA Dermatology, researchers from the Republic of Korea investigated whether having a history of coronavirus disease 2019 (COVID-19) increased the long-term risk of autoimmune and autoinflammatory connective tissue disorders.

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PIER MARIA FORNASARI
2024-10-25

18-month data suggest myocarditis complications more common after COVID infection than vaccination

A study today in JAMA suggests that hospitalized patients—primarily previously healthy young men—have considerably fewer cardiovascular sequelae by 18 months if they develop myocarditis after COVID-19 mRNA vaccination than after COVID-19 infection. French researchers mined data from the French National Health Data System on all 4,635 residents aged 12 to 49 years hospitalized for myocarditis, or inflammation of the heart

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PIER MARIA FORNASARI
2024-10-14

Wider Use of Convalescent Plasma Might Have Saved Thousands More Lives During Pandemic

Authors say findings support considering convalescent plasma deployment for future infectious diseases emergencies A new study led by researchers at Johns Hopkins Bloomberg School of Public Health estimates that thousands of lives could have been saved during the first year of the COVID-19 pandemic if convalescent plasma had been used more broadly, particularly in outpatients

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PIER MARIA FORNASARI
2024-09-26

Antiviral-Resistant Variants of SARS-CoV-2 Can Emerge in Immunocompromised People

Researchers isolated SARS-CoV-2 strains, which are drug resistant with mutations to the nsp12 protein that is the target of remdesivir and another variant with mutations to the nsp5 protein, the target of Paxlovid. These mutations help the virus persist in people with compromised immunity despite common antiviral treatments. Individuals with compromised immunity and persistent COVID-19

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PIER MARIA FORNASARI
2024-06-22

Immune response study explains why some people don’t get COVID-19

Using single-cell sequencing technology, researchers provide the most comprehensive timeline to date of how the body responds to SARS-CoV-2 exposure. Scientists have discovered novel immune responses that help explain how some individuals avoid getting COVID-19. Using single-cell sequencing, researchers from the Wellcome Sanger Institute, University College London (UCL), Imperial College London, the Netherlands Cancer Institute

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PIER MARIA FORNASARI
2024-06-22

Suppression of Type I Interferon Signaling in Myeloid Cells by Autoantibodies in Severe COVID-19 Patients

Even though COVID-19 manifests as a mild and short-lived disease in most people, some suffer extremely severe symptoms; in the worst cases, these patients die due to complications such as respiratory failure or thromboembolism. It is well-known that factors such as age and underlying medical conditions like diabetes or immunodeficiencies increase vulnerability to severe COVID-19.

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