Discovery made while editing genetic defect behind Duchenne muscular dystrophy Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases. The finding stemmed from research at UT Southwestern in which a single-cut gene-editing
Researchers used time-lapse imaging to show that mouse induced pluripotent stem cells (iPSCs) grown during spaceflight differentiated into cardiomyocytes significantly faster than similar cells grown at Earth’s gravity. The robust cardiomyocyte formation at microgravity, which lasted for 10 days, is described in an article published in Stem Cells and Development, a peer-reviewed journal from Mary Ann Liebert,
A team of researchers from Northwestern University designed a new wireless sensor for neonatal babies that can track vitals. Researchers at Northwestern University have developed a new wearable sensor for newborns that is being pitched as an alternative to the traditional wire technology, which can prevent babies from being held. The system’s two sensors also
Cell sheets have previously shown greater efficacy for tissue repair than injections of single stem cells. New research conducted by scientists at the Los Angeles Biomedical Research Institute and Emmaus Life Sciences, Inc. (both CA, USA) has demonstrated the possibility of producing scaffold-free engineered cell sheets. These cell ‘patches’ could enable better organ repair follow
In a paper published in the journal Nature, an international research team led by researchers at Karolinska Institutet in Sweden report that bone growth in mice takes place in accordance with the same principles as when new cells are constantly produced in blood, skin and other tissue. This contradicts the previous understanding that bone growth depends
01 March 2019 P.M.Fornasari While the advent of 3D printers is commonly thought of as a revolution for manufacturing, it could have huge benefits for medicine as well. To help patch up large wounds that might normally require a skin graft, researchers at Wake Forest Institute for Regenerative Medicine (WFIRM) have developed a new bioprinter
Advanced Therapies are new treatment modalities (e.g. cell and gene therapy, tissue engineering) that aim to consign the never-ending treatment of chronic ailments to the past and instead offer sustained improvement and even cures. To enable Europe to become a competitive leader in this field, RESTORE is defining an Advanced Therapies roadmap 2021-2030 for Europe.
01 MARCH 2019 P.M.Fornasari On average, people are living longer than ever before, and that’s good news. However, ageing populations mean higher rates of certain illnesses, such as neurodegenerative disorders. A prominent example of is Parkinson’s disease, a medical condition that already affects 6.5 million people worldwide. This number is expected to more than double
01 March 2019 P.M.Fornasari Rare diseases affect fewer than roughly five in 10,000 people worldwide. Approximately 80% of rare diseases have identified genetic origins, and are often debilitating; about 30% of children with a rare disease will die before their fifth birthday. There are roughly 30 million people in the U.S. living with a rare
March 1 2019 P.M. Fornasari “Certain patients with cancer may require surgical procedures to treat or prevent the spread of cancer in their body. These procedures are often associated with improved survival outcomes for these patients. However, today we are warning patients and providers that the use of robotically-assisted surgical devices for any cancer-related surgery
