The partnership between the US software giant and UK-based biotech company is designed to increase the yield and improve the purity of lentiviral vectors in gene therapy. A British cell and gene therapy company is partnering up with the world’s largest software company to improve gene therapy vectors using cloud computing and machine learning. Oxford,
Eric Lander, Françoise Baylis, Feng Zhang, Emmanuelle Charpentier, Paul Berg and specialists from seven countries call for an international governance framework. We call for a global moratorium on all clinical uses of human germline editing — that is, changing heritable DNA (in sperm, eggs or embryos) to make genetically modified children. By ‘global moratorium’, we
NIH-funded discovery uses common antifungal drug to improve lungs’ ability to fight infection. Researchers say a widely-used antifungal drug may hold promise for treating people with cystic fibrosis, a life-threatening genetic disorder that causes serious damage to the lungs. In studies using human cells and animals models, the researchers found that the medication, called amphotericin,
NASA’s Human Research Program releases “Metabolomics: You Are What You Eat” video to highlight its Twins Study which uses omics to study Mark and Scott Kelly’s metabolites. Omics is an evolving field integrating collections of measurements, biomolecules and sub-disciplines to provide a more complete picture of health.
Lipidomics, the comprehensive analysis of a cell or organism’s lipid profile, is a subgroup within the field of metabolomics that is rapidly developing into a discipline of its own. Until recently, a common misconception was that lipids are simply fat molecules, however, recent advances in technologies used to dissect and study lipid profiles prove that
Sharp rise in obesity, anemia among adolescents worldwide Nearly a billion young people across the world are living in countries where they face multiple health burdens, a jump of more than 250 million from nearly two decades ago, according to new research. Here’s a rundown of the study: The design: The authors looked at changes across 195
Here’s why that’s undermining personalized medicine In a paper published last week, scientists led by Dr. Pui-Yan Kwok of the University of California, San Francisco, analyzed 154 genomes from 26 ethnic populations, from Han Chinese and Tuscans to Yoruba, Esan, Puerto Ricans, and Peruvians. They found 60 million bases in one or more of these populations
Researchers invent a resistance-sensing injection device that knows where to go Syringes and hollow needles—among the most feared and most commonly used tools in medical practice—have been around for more than a century. However, the precise insertion of these devices depends largely on the technique and skill of the person delivering the injection. And some anatomical
Molecular pathway plays major role in the intersection between aging and heart failure A team led by Harvard Medical School researchers based at Massachusetts General Hospital has found that activity of an important signaling pathway increases with aging and with heart failure. In a report published in Science Translational Medicine, the team describes evidence from both humans
A feature-length documentary chronicling the story of CRISPR premiered at the SXSW festival yesterday. From executive producer Dan Rather and director Adam Bolt, the co-writer and editor of the Oscar-winning film Inside Job, comes the story of the biggest tech revolution of the 21st Century. And it isn’t digital, it’s biological. A breakthrough called CRISPR has
