A predictive machine learning model was able to identify how effectively patients with Crohn’s disease would respond to long-term usage of ustekinumab, according to a new study in JAMA Network Open. Researchers from the University of Michigan trained the model using demographic and laboratory data obtained in previous clinical trials. The data described 401 patients with active Crohn’s
By the time they reach school age, about 90 percent of children will have experienced a condition in which fluid fills the middle ear, muffling sound and sometimes triggering infection. Diagnosis usually requires a visit to a specialist—but researchers have now developed an app that detects this fluid just as accurately, with only a smartphone
For the first time, immunologists from The University of Texas at Austin have captured on video what happens when T-cells – the contract killers of the immune system, responsible for wiping out bacteria and viruses – undergo a type of assassin-training program before they get unleashed in the body. A new imaging technique that allowed
Only about 25 percent of U.S. patients survive when their hearts stop in hospitals. Crucial minutes elapse before help arrives, sometimes because alarms are missed amid the din of beeping monitors. But the call that day didn’t come from within the hospital. It came from a darkened room in an office park several miles away, where a
A new ‘biological glue’ developed by Chinese researchers could one day stop hearts and arteries from uncontrollable bleeding. Placed on an open wound and activated through UV light, this life-saving sealant rapidly morphs into a non-toxic hydrogel, capable of withstanding both slippery surfaces and the pulsing of heart tissue. The adhesive sealant hasn’t been tested
For more than a decade now, since 2008 when Marvel Studio’s Iron Man debuted, pop culture fans have been fascinated by the idea of people donning robot parts to be stronger or faster. Medicine and technology teaming up to enhance physical ability is not new, either, with several generations of both theory and application finding success. Until
People eating ultra-processed foods ate more calories and gained more weight than when they ate a minimally processed diet, according to results from a National Institutes of Health study. The difference occurred even though meals provided to the volunteers in both the ultra-processed and minimally processed diets had the same number of calories and macronutrients.
Researchers at The Royal Marsden say ctDNA, a form of liquid biopsy, may be an accurate technique to monitor treatment response in patients with locally advanced rectal cancer, allowing treatment to be adapted or changed earlier to try to prevent the development of metastatic disease. Results from the study, led by researchers at The Royal
While therapies that harness the power of the immune system against cancer have made remarkable progress against certain types of tumours, they still remain ineffective in most cancer patients. A new study has described a method of reprogramming the regulatory T cells that usually suppress immune responses into inflammatory cells that not only permit but
New WHO Guidelines recommend specific interventions for reducing the risk of cognitive decline and dementia People can reduce their risk of dementia by getting regular exercise, not smoking, avoiding harmful use of alcohol, controlling their weight, eating a healthy diet, and maintaining healthy blood pressure, cholesterol and blood sugar levels, according to new guidelines issued
