PIER MARIA FORNASARI

PIER MARIA FORNASARI
2019-05-16

Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle

Researchers of the Stanford University College of Medicine have just published an important paper on FAP mesenchymal stromal cells in muscle regeneration. The necessity of mesenchymal stromal cells, called fibroadipogenic progenitors (FAPs), in skeletal muscle regeneration and maintenance remains unestablished. We report the generation of a PDGFRαCreER knockin mouse model that provides a specific means of

No Comments InREGENERATIVE MEDICINE

PIER MARIA FORNASARI
2019-05-16

Gene expression signatures of Alzheimer’s disease

Alzheimer’s disease is an irreversible brain disorder that affects more than 5 million Americans. It slowly worsens and destroys memory and thinking skills. Previous research has linked memory and thinking problems with visible changes that take place in the brain. People with Alzheimer’s have abnormal deposits of proteins called amyloid plaques and tau tangles. Plaques

No Comments InWELLNESS

PIER MARIA FORNASARI
2019-05-16

Targeting Huntingtin Expression and Gene Therapy in Patients with Huntington’s Disease

Data presented at the American Academy of Neurology (AAN) meeting this week on experimental therapeutics for Huntington’s disease gave some cause for optimism. And, as good research does, they identified new questions as they answered current ones. At the meeting, researchers presented new data on antisense oligonucleotide HTTRx (RG-6042, Ionis Pharmaceuticals Inc./Roche Holding AG) that

No Comments InGENE THERAPY RARE DISEASES

PIER MARIA FORNASARI
2019-05-14

Most Healthcare, Fitness Tracker, And Wellness Apps Are Not Covered By HIPAA And HHS’s New Faqs Makes That Clear

Individuals who use healthcare apps such as fitness trackers, weight loss, wellness, exercise, etc., BEWARE!A couple of recent developments have highlighted the fact that most apps are not subject to HIPAA, which means that with broadly-worded privacy policy these healthcare apps can and do readily share healthcare and other data collected by the apps with third

No Comments InDIGITAL HEALTH

PIER MARIA FORNASARI
2019-05-14

Blocking protein curbs memory loss in old mice

Impeding VCAM1, a protein that tethers circulating immune cells to blood vessel walls, enabled old mice to perform as well on memory and learning tests as young mice, a Stanford study found. Mice aren’t people, but like us they become forgetful in old age. In a study published online May 13 in Nature Medicine, old mice suffered far

No Comments InWELLNESS

PIER MARIA FORNASARI
2019-05-14

Letter to the Duchenne Community: Gene Therapy IGNITE DMD Status and New Clinical Sites

Dear Duchenne Community, We want to provide you with an update on the progress of SolidBiosciences IGNITE DMD Phase I/II clinical trial for our investigational microdystrophin gene transfer, SGT-001. Since we communicated preliminary clinical data in February, we advanced the study to evaluate SGT-001 at a higher dose in the second cohort of patients. As

No Comments InGENE THERAPY RARE DISEASES

PIER MARIA FORNASARI
2019-05-14

FDA Breakthrough Device Designation to Multi-Cancer Early Detection Test

GRAIL, Inc., a healthcare company whose mission is to detect cancer early, when it can be cured, today announced that its multi-cancer test has been granted Breakthrough Device designation from the U.S. Food and Drug Administration (FDA). The investigational blood test is in development for the early detection of multiple cancer types in individuals aged

No Comments InWELLNESS

PIER MARIA FORNASARI
2019-05-14

Artificial intelligence could select heart failure patients for expensive treatment

Machine learning algorithm predicts sudden death in heart failure patients for the first time Artificial intelligence (AI) has shown promise to select heart failure patients for expensive treatments to prevent lethal arrhythmias, reports a study presented today at ICNC 2019. (1) The study is the first to use a machine learning algorithm to predict sudden

No Comments InARTIFICIAL INTELLIGENCE

PIER MARIA FORNASARI
2019-05-14

German Ethics Council: germline interventions currently too risky, but not ethically out of the question

Last year, the birth of the first genetically modified babies shook the world. The German Ethics Council now presents a comprehensive ethical investigation into possible interventions in the genome of human embryos or germ cells. The Council does not deem the human germline to be inviolable. It does, however, consider germline interventions to be ethically

No Comments InGENOME Uncategorized

PIER MARIA FORNASARI
2019-05-13

Negative clinical trials: stem cells in heart failure

Despite the binary thinking of progressive scientists on the one hand and prophets of doom on the other, science doesn’t tend towards good or evil. Any experiments scientists can do, they will. This is a positive thing, because who is a position to claim omniscience and to forbid it? In fact, it’s human beings who

No Comments InREGENERATIVE MEDICINE

REGENERATIVE AND PERSONALISED MEDICINE

DIGITAL HEALTHCARE

All posts by PIER MARIA FORNASARI

Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle

Gene expression signatures of Alzheimer’s disease

Targeting Huntingtin Expression and Gene Therapy in Patients with Huntington’s Disease

Most Healthcare, Fitness Tracker, And Wellness Apps Are Not Covered By HIPAA And HHS’s New Faqs Makes That Clear

Blocking protein curbs memory loss in old mice

Letter to the Duchenne Community: Gene Therapy IGNITE DMD Status and New Clinical Sites

FDA Breakthrough Device Designation to Multi-Cancer Early Detection Test

Artificial intelligence could select heart failure patients for expensive treatment

German Ethics Council: germline interventions currently too risky, but not ethically out of the question

Negative clinical trials: stem cells in heart failure