Nomenclature and heterogeneity: consequences for the use of mesenchymal stem cells in regenerative medicine

Source Future Medicine Mesenchymal stem cells (MSCs) are in development for many clinical indications, based both on ‘stem’ properties (tissue repair or regeneration) and on signaling repertoire (immunomodulatory and antiinflammatory effects). Potential conflation of MSC properties with those of tissue-derived stromal cells presents difficulties in comparing study outcomes and represents a source of confusion in

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Graphene 3D printing

As discoveries around graphene applications abound, many are wondering if it can be scaled to 3D. This could have revolutionary effects, but it begs the question, have scientists been successful in graphene 3D printing? Find out! GRAPHENE 3D PRINTING Is It Possible? So, is it possible to 3D print graphene? The short answers is, not

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US Researchers Continue to Improve 3D Printed Prosthetics for Children

US researchers from the University of Central Florida and Oregon Health and Science University have come together to review the history not only of prosthetics overall in the medical field but also to further inspect the transformation allowed by 3D printing. Contending that there are still many problems to be solved in prosthetics, the authors further explore children’s physical

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New International Commission Launched on Clinical Use of Heritable Human Genome Editing

An international commission has been convened by the U.S. National Academy of Medicine (NAM), the U.S. National Academy of Sciences (NAS), and the Royal Society of the U.K., with the participation of science and medical academies around the world, to develop a framework for scientists, clinicians, and regulatory authorities to consider when assessing potential clinical

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Establishing Manufacturing Controls: A Hurdle for the Cell and Gene Therapy Industry

Source RAPS Addressing manufacturing controls for the cell and gene therapy industry, this article discusses criticality of establishing Chemistry Manufacturing Controls (CMC) Readiness, Critical Quality Attributes (CQAs) and Critical Process Parameters (CPPs) for cell and gene therapy products. The author suggests manufacturers need sound drug development and manufacturing facility plans covering a product’s lifecycle and

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Millions of Europeans at risk of chronic digestive diseases, new report reveals

Source  United European Gastroenterology Poor nutritional choices, including a high intake of ultra-processed foods and trans-fats, are putting millions of Europeans at an increased risk of a range of chronic digestive diseases, including digestive cancers, wheat related disorders and functional GI disorders, as well as obesity, a new report shows. Nutrition and Chronic Digestive Diseases,

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New tools for new treatments

Source Nature From antibiotics and organoids to CRISPR, improved biomedical methods and apparatus are enabling new therapies. Organoids Mini organs stand in for test models The term ‘organoid’ didn’t exist a decade ago. Now it’s a buzzword in biomedical science for a three-dimensional multi-cellular structure or ‘mini organ’. Thanks to advances with pluripotent stem cells

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