In a recent decision (Ra 2015/11/0113), the Austrian Supreme Administrative Court (VwGH) inter aliaaddressed the question whether the application of stem cell therapy violates Section 49 of the Austrian Act on the Medical Profession (Ärztegesetz, ÄrzteG), which requires physicians to treat patients “… in accordance with state of the art medical science and practice” and to at all
Source BIOPROCESS ONLINE Innovation in gene therapy brings the potential for transforming patient care and obviating the need for chronic therapy through single-dose cures. Despite the potential long-term benefits of this new therapeutic modality, gene therapy companies face a number of underappreciated challenges. While there have been recent curative achievements in hepatitis C virus, curative
The U.S. Food and Drug Administration today approved Emgality (galcanezumab-gnlm) solution for injection for the treatment of episodic cluster headache in adults. “Emgality provides patients with the first FDA-approved drug that reduces the frequency of attacks of episodic cluster headache, an extremely painful and often debilitating condition,” said Eric Bastings, M.D., deputy director of the
Source NIH With advances in induced pluripotent stem cell (iPSC) technology, it’s now possible to reprogram adult skin or blood cells to form miniature human organs in a lab dish. While these “organoids” closely mimic the structures of the liver and other vital organs, it’s been tough to get them to represent inflammation, fibrosis, fat
Researchers funded by British Heart Foundation have shown that heart ‘patches’ grown in the lab are safe to move on to trials in people with hearts damaged after a heart attack, in research presented at the British Cardiovascular Society (BCS) Conference in Manchester today. These patches could one day cure debilitating heart failure, which affects
Authors Ghadge Snehal, Aloorkar Nagesh, and Sudake Suresh from the Satara College of Pharmacy explore 3D printing of medication, and the possibilities for the future in ‘A Decisive Overview on Three Dimensional Printing in Pharmaceuticals.’ The researchers realize the enormous impact 3D printing is having worldwide, offering truly infinite power for innovation—with a tremendous focus on the
Source Elsevier One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo. In this important review in Digestive and Liver Disease, published by Elsevier, scientists highlight some of the established and exciting novel uses for organoids or
Expanded Potential Stem Cell lines of pig and human cells established A new approach has enabled researchers to create Expanded Potential Stem Cells (EPSCs) of both pig and human cells. These stem cells have the features of the very first cells in the developing embryo, and can develop into any type of cell. The research
Reviews Gene Editing for Immune Cell Therapies Autologous T cells that have been genetically modified to express a chimeric antigen receptor targeting the B cell antigen CD19 have yielded remarkable clinical responses in patients with B cell malignancies, and are now on the market as anticancer ‘drugs’. [Nat Biotechnol] Abstract The Next Generation of CRISPR-Cas Technologies
MIT startup Inkbit is overcoming traditional constraints to 3-D printing by giving its machines “eyes and brains.” Objects made with 3-D printing can be lighter, stronger, and more complex than those produced through traditional manufacturing methods. But several technical challenges must be overcome before 3-D printing transforms the production of most devices. Commercially available printers
