Activity trackers and mobile phone apps are all the rage, but do they really help users increase and maintain physical activity? A new study has found that one mobile phone app designed for inactive women did help when combined with an activity tracker and personal counseling. Researchers said the findings offer important clues about how
Bone defects caused by various aetiologies, such as trauma, tumours, infection and congenital deformities, together with articular cartilage defects and osteochondral complex defects caused by trauma and degenerative diseases, are common clinical diseases that significantly affect the patient’s quality of life. Repair and regenerating these defects in bone and cartilage is a considerable challenge for
Researchers of the Institute of Neurophysiology and Centre for Molecular Medicine Cologne (CMMC), University of Cologne (UKK) and Leibniz Research Centre for Working Environment and Human Factors, Technical University of Dortmund (IfADo) have just published a paper in Trends in Molecular Medicine showing that hiPSC differentiation protocols theoretically offer the prospect of an unlimited supply
Whether hippocampal neurogenesis persists throughout life in the human brain is not fully resolved. Researchers of the Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, USA demonstrate in a just published paper on Cell Stem Cell that hippocampal neurogenesis is persistent through the tenth decade of life and is detectable
Meaningful studies are lacking for certain patient groups / Disease-specific registries could help close the data gap The German Institute for Quality and Efficiency in Health Care (IQWiG) has investigated whether patients suffering from non-Hodgkin lymphoma have (better) chances of recovery when stem cells from another person are transplanted. In its final report now presented,
Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have shown the feasibility of bioengineering vascularized functional renal tissues for kidney regeneration, developing a partial augmentation strategy that may be a more feasible and practical approach than creating whole organs. In the proof-of-concept study published online this month in Acta Biomaterialia journal, the scientists created a novel
A number of physiological and psychological changes occur as we age, and many studies have shown that our gut microbiome also changes as we grow older. A fascinating new study is suggesting that a shift in gut bacteria in our middle-age could trigger a process that plays a role in cognitive decline in our later years. And
York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation that could lead to new therapeutic targets to prevent the spread of muscle cancer. The researchers analyzed gene networks in muscle cells and found that the Smad7 and β-catenin proteins work co-operatively inside the
Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials. However, other than observing clinical outcomes, lack of a repeatable, time-sensitive and noninvasive tool to assess the effectiveness of the transplanted cells within the target organ has slowed progress in the stem cell field.
Johns Hopkins researchers have developed a way to map retinal cell development and potentially advance regenerative medicine Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells. The technique, demonstrated in mouse retinas for this study, follows the activity of
