Evidence of haemorrhages in fetal brain tissue associated with the presence of SARS-CoV-2

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has found evidence of small haemorrhages in fetal brain tissue during the peak of COVID-19 cases in the UK. The research, published in Brain, found that the haemorrhages are linked to a reduction in blood vessel integrity. The cause of these

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Cornell University study identifies four major subtypes of long COVID

The post-COVID syndrome known as long COVID has four major subtypes defined by different clusters of symptoms, according to a study led by researchers at Weill Cornell Medicine. The study, published Dec. 1 in Nature Medicine, was the largest of its kind to examine long COVID. The researchers, who represent clinicians and informaticists, used a machine-learning algorithm

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Middle-age high normal serum sodium as a risk factor for accelerated biological aging, chronic diseases, and premature mortality: good hydration linked to healthy aging

NIH findings may provide early clues about increased risks for advanced biological aging and premature death. Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine(link

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Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in moderate-severe COVID-19

A study by Imperial College London, in the United Kingdom, shows an irregular activity of monocytes with a prothrombotic effect Among the complications most attributed to Covid-19 is thrombosis. The formation of blood clots in the veins or arteries in the weeks following the coronavirus infection , impairing blood circulation, was one of the symptoms seen frequently among patients around

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In Shanghai, up to 70% 25 million population may have been infected with COVID-19

A senior doctor at one of Shanghai’s top hospitals says 70 per cent of the megacity’s population may have already been infected with COVID-19 during China’s huge surge in cases, state media are reporting. Key points: The steep rise in infections came after years of hardline restrictions were abruptly loosened last month, with little warning or

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NIH clinical trial leads to atezolizumab approval for advanced alveolar soft part sarcoma

A clinical trial led by the National Cancer Institute (NCI), part of the National Institutes of Health, has resulted in the first approval of a treatment for advanced alveolar soft part sarcoma (ASPS). The immunotherapy drug atezolizumab (Tecentriq) was recently approved by the U.S. Food and Drug Administration (FDA)(link is external) for the treatment of adults and

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Coadministration of CD19- and CD22-Directed Chimeric Antigen Receptor T-Cell Therapy in Childhood B-Cell Acute Lymphoblastic Leukemia: A Single-Arm, Multicenter, Phase II Trial with a 99% response rate

An innovative immunotherapy combination has shown a stunning 99% response rate in children with relapsed leukemia. The phase 2 trial, run jointly between researchers at St. Jude Children’s Research Hospital in Memphis and Shanghai Children’s Hospital in China tested the therapy in 225 children who had relapsed after conventional treatment. The work published in the Journal

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China’s COVID-19 wave forecast to have two peaks where cases could reach 4.2 million a day: ew modelling by Airfinity examining data from China’s regional provinces

China is predicted to see two peaks in cases as COVID-19 spreads throughout the country, the first peak in mid-January and the second in early March.  New modelling by Airfinity has examined data from China’s regional provinces. The current outbreak is growing more rapidly in some regions than in others. Cases are currently rising much

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