Damage to joint cartilage is painful and limits mobility. Researchers at the University of Basel and the University Hospital of Basel are therefore developing cartilage implants from cells from the nasal septum. A recent study shows that a longer maturation time for the cultured cartilage brings a significant improvement even in cases of complicated cartilage
Pioneering prosthetic hand carefully conforms and adjusts its grasp to avoid damaging or mishandling whatever it holds Key Takeaways Johns Hopkins University engineers have developed a pioneering prosthetic hand that can grip plush toys, water bottles, and other everyday objects like a human, carefully conforming and adjusting its grasp to avoid damaging or mishandling whatever
Alzheimer disease (AD), the most common cause of cognitive impairment, is characterized by β-amyloid (Aβ) plaques and tau neurofibrillary tangles, which lead to neuroinflammation, neurodegeneration, and cognitive decline. Among various interventions, physical activity (PA) is widely recommended. Numerous studies suggest that PA not only slows cognitive decline but also improves specific cognitive functions. Potential mechanisms underlying the protective
Adding a personalised mRNA vaccine to plain remedy might supply new hope for pancreatic cancer sufferers, a small but promising study from Memorial Sloan Kettering Cancer Center. The study adopted 16 sufferers, together with Barbara Brigham, who joined the trial after a routine scan found her early-stage pancreatic cancer. Alongside surgical procedure and chemotherapy, sufferers
The use of semaglutide (Ozempic) was tied to a risk of nonarteritic anterior ischemic optic neuropathy (NAION) in adults with type 2 diabetes, according to a retrospective study. In this review of 37.1 million patients, the incidence rate of NAION among semaglutide users was 14.5 and 8.7 per 100,000 person-years using the sensitive and specific
A bone marrow transplant process co-developed by investigators at the Johns Hopkins Kimmel Cancer Center is safe and curative for adults with sickle cell disease, according to results of a trial completed at Johns Hopkins and about 20 additional cancer centers nationwide and in London. The treatment, available at multiple U.S. medical centers, is a viable and
Researchers from the University of Twente’s TechMed Centre and Radboud University Medical Centre removed blood clots using wireless magnetic robots. This innovation could revolutionise the treatment of life-threatening vascular diseases such as thrombosis. Cardiovascular diseases such as thrombosis are a major health problem worldwide. Worldwide, one in four people die each year from conditions caused
Researchers from the NIHR Moorfields Biomedical Research Centre and University College London have found that gene therapy improved visual acuity and preserved retinal structure in young children with AIPL1-associated severe retinal dystrophy. This is the first human trial of gene supplementation therapy targeting this condition. Retinal dystrophy caused by biallelic variants in the AIPL1 gene
An 18-year survivor of neuroblastoma, a solid childhood tumor that develops in immature nerve cells, is believed to represent the longest reported remission to date in a patient treated with chimeric antigen receptor (CAR) T cell therapy. The findings, published in Nature Medicine, describe several long-term survivors in a follow-up from a phase 1 clinical trial
GLP-1 medications initially were used to help people with diabetes improve their insulin resistance and hunger cravings. However, over the past few years, these medications have become popular due to their weight loss and weight management benefits. Outside of nutrition, physical activity and surgery, Dr. Saundra Nguyen, assistant professor of internal medicine at Baylor College of Medicine, explaining
