Expanded Potential Stem Cell lines of pig and human cells established A new approach has enabled researchers to create Expanded Potential Stem Cells (EPSCs) of both pig and human cells. These stem cells have the features of the very first cells in the developing embryo, and can develop into any type of cell. The research
Reviews Gene Editing for Immune Cell Therapies Autologous T cells that have been genetically modified to express a chimeric antigen receptor targeting the B cell antigen CD19 have yielded remarkable clinical responses in patients with B cell malignancies, and are now on the market as anticancer ‘drugs’. [Nat Biotechnol] Abstract The Next Generation of CRISPR-Cas Technologies
MIT startup Inkbit is overcoming traditional constraints to 3-D printing by giving its machines “eyes and brains.” Objects made with 3-D printing can be lighter, stronger, and more complex than those produced through traditional manufacturing methods. But several technical challenges must be overcome before 3-D printing transforms the production of most devices. Commercially available printers
Michigan State University physicians have found that vitamin D, if taken for at least three years, could help cancer patients live longer. The findings suggest that the vitamin carries significant benefits other than just contributing to healthy bones and were presented at the American Society of Clinical Oncology annual meeting on June 3, 2019. In
ZYNTEGLO is the first gene therapy approved for transfusion-dependent β-thalassemia (TDT) European marketing authorization for ZYNTEGLO follows the fastest assessment of an advanced therapy medicinal product (ATMP) as part of the European Medicines Agency’s Priority Medicines (PRIME) program ZYNTEGLO is bluebird bio’s first gene therapy to gain regulatory approval bluebird bio, Inc. announced today that the European Commission (EC)
Source: Nature Study of almost half a million people links mutation that protects against HIV infection to an earlier death. The scientist who edited the genomes of twin girls in an attempt to make them resistant to HIV might have inadvertently shortened their life expectancy. People with two disabled copies of the CCR5 gene — the version
Scientists have successfully 3D printed a cornea utilizing a biocompatible bioink, composed of decellularized corneal stroma and stem cells, resulting in a replica with transparency similar to a human cornea. A collaborative team of engineering and medical scientists from the Pohang University of Science and Technology (Republic of Korea) have developed a strategy for 3D
Novel molecules developed by researchers at the Rockefeller University (NY, USA) have the potential to provide treatments for the millions of people who suffer from an autoimmune disorder. Reported recently in Nature Communications, Thomas Tuschl (Professor at Rockefeller University; NY, USA) and his fellow researchers from have developed small molecules that can bind to and inhibit one
While wrist-worn wearables accounted for the majority of the market with 63.2% share, ear-worn devices experienced the fastest growth (135.1% YoY). Global shipments of wearable devices reached 49.6 million units during the first quarter of 2019, up 55.2% from the previous year according to data from the International Data Corporation (IDC) Worldwide Quarterly Wearable Device
The US Food and Drug Administration (FDA) has approved Piqray (alpelisib) tablets to treat patients with breast cancer. Piqray is to be used in combination with the FDA-approved endocrine therapy, fulvestrant, to treat post-menopausal patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer (as detected by
