The Mitochondrion as an Emerging Therapeutic Target in Cancer
Source https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(19)30171-6 Mitochondria display a dynamic and heterogeneous phenotype that facilitates the metabolic heterogeneity and plasticity of cancer cells. The altered metabolic functions and dynamics of mitochondria in cancer cells, as well as mitochondrial evasion of apoptosis, provide targets for novel cancer therapeutics. The mitochondrial network has distinct morphological features that appear to be interrelated