New disease could provide insights into how the cell’s recycling system contributes to a healthy brain. Researchers at the National Institutes of Health have discovered a new neurological condition characterized by issues with motor coordination and speech. They report their findings in npj Genomic Medicine. Scientists from NIH’s National Human Genome Research Institute (NHGRI) and Undiagnosed
A team led by McMaster University researchers Gilmar Reis and Edward Mills has discovered that a single injection of pegylated interferon lambda can successfully treat COVID-19 in people early in the disease. A team led by McMaster University researchers Gilmar Reis and Edward Mills has discovered that a single injection of pegylated interferon lambda (lambda)
A team of medical specialists working at Memorial Sloan Kettering Cancer Center in New York has found that donated white blood cells can be used effectively as part of CAR T cell therapy to treat myeloma patients. In their study, published in the journal Nature Medicine, the group gave patients varying amounts of donated CAR T cells
By addressing molecules governing how host cells respond to the SARS-CoV-2 virus, researchers hope they’ve found a new therapeutic target less vulnerable to potential drug resistance and emerging variants of concern Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human
What New research offers clues about the biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. A team of researchers supported by the National Institutes of Health found evidence linking motor neurons’ large cell size and supporting structure with the genes that underlie their vulnerability
A new blood product combining red blood cells and plasma in one bag is associated with a better survival from a penetrating major trauma injury, a new study involving Queen Mary University of London has found. NHS Blood and Transplant, Queen Mary University London, and Barts Health NHS Trust collaborated on the new study published in
The U.S. Food and Drug Administration approved Jesduvroq tablets (daprodustat) as the first oral treatment for anemia (decreased number of red blood cells) caused by chronic kidney disease for adults who have been receiving dialysis for at least four months. Jesduvroq is not approved for patients who are not on dialysis. Other FDA-approved treatments for
Blocking an immune-regulating protein reverses the damage caused by acute and chronic kidney disease, a preclinical study suggests. Led by scientists at Duke-NUS Medical School and the National Heart Centre Singapore, researchers in Singapore and Germany have found that renal tubular cells, which line the tiny tubes inside kidneys, release a scar-regulating protein called interleukin-11
In recent months there have been some major jumps—unprecedented success stories—that indicate our ability to engineer T cells may well have a substantial impact for multiple medical conditions that have not been responsive to conventional therapies or for which there is no available treatment. This can be regarded as the quintessential individualized medicine intervention—specifically modifying
Once weekly efanesoctocog alfa provides superior bleeding prevention to prestudy prophylaxis for patients with severe hemophilia A, according to a study published in the Jan. 26 issue of the New England Journal of Medicine. Annette von Drygalski, M.D., Pharm.D., from the University of California in San Diego, and colleagues conducted a phase 3 study involving patients
