Wake Forest Institute for Regenerative Medicine scientists have fine-tuned their delivery system to deliver a DNA editing tool to alter DNA sequences and modify gene function. The improved “hit and run” system works faster and is more efficient. “With this new method we are able to package together in one lentiviral capsid both essential components
In ‘Synthesis, characterization and 3D printing of linear and star-shaped poly(propylene fumarate) for medical applications,’ Yuanyuan Luo offers a PhD dissertation for The University of Akron on the subject of additive manufacturing and new polymer synthetics for use in the medical realm. As materials science continues to expand, researchers are drawn to exploring the uses of 3D
We often take our immune and nervous systems for granted. We assume that our immune system will protect us from diseases and when pathogens invade our body. Likewise, we assume that our nervous system will take information from the environment, relay it to our brain and then allow our brain to move muscles. But what
Monash University researchers, along with industry partner Haemokinesis, have developed the world’s first blood incubator using laser technology. This technology can slash blood incubation time to just 40 seconds, compared to the current industry gold standard of five minutes. The study shows that laser incubation can improve pre-transfusion testing for millions of patients undergoing blood
Both digital and genomics biomarkers are important in diagnosing and treating disease. Apple is playing a key role in driving this revolution by crowdsourcing patient-level data through its Apple Watches. Apple’s Apple Research app will join with the Apple Watch and the iPhone to crowdsource health data for future research. Those with an Apple Watch will be able
By exploiting a feature of the immune system, researchers open the door for stem cell transplants to repair the brain. In experiments in mice, Johns Hopkins Medicine researchers say they have developed a way to successfully transplant certain protective brain cells without the need for lifelong anti-rejection drugs. A report on the research, published Sept. 16 in
At the Association for Glycogen Storage Disease’s 41st Annual Conference, Dr. David Weinstein of UConn School of Medicine and Connecticut Children’s presented his groundbreaking, one-year clinical trial results for the novel gene therapy treatment for glycogen storage disease (GSD). The rare and deadly genetic liver disorder, GSD type Ia, affects children from infancy through adulthood, causing dangerously
In the body’s cells, some proteins are of vital importance as to which genes are active or turned off. Now, researchers from the University of Copenhagen and the Memorial Sloan Kettering Cancer Center have discovered which proteins are necessary in order to maintain the proper genetic regulation. All of the more than 200 different cell
Long-Term Follow-up Data Show That the 88% of Patients Treated in the Starbeam Study (ALD-102) Were Free of Major Functional Disabilities (MFDs) at Two Years, and Continued to Remain MFD-Free at up to Five Years of Follow-up bluebird bio, Inc. (Nasdaq: BLUE) today announced updated results from the clinical development program for its investigational Lenti-D™ gene
Source Cancer Network Several promising drugs for the treatment of lung cancer have been garnering attention over recent years. These new treatments have been highlighted at conferences and are sure to impact the standard of care. Some of these new treatments are detailed below. LOXO-292 Various multikinase inhibitors (MKI) with some activity against RET have
