Treatment uses person’s own stem cells instead of donor cells UCLA researchers are part of an international team that reported the use of a stem cell gene therapy to treat nine people with the rare, inherited blood disease known as X-linked chronic granulomatous disease, or X-CGD. Six of those patients are now in remission and
Mount Sinai surgeons have performed the first-ever spinal tethering surgery in New York City to correct idiopathic scoliosis—a sideways curvature in the spine—in children and adolescents. The procedure performed by Baron S. Lonner, MD, Professor of Orthopedic Surgery, and Pediatrics, Icahn School of Medicine at Mount Sinai, and Chief of Minimally Invasive Scoliosis Surgery, Mount
Elsevier has set up an Information Centre on the newly emerged coronavirus featuring in the current outbreak in China, with free information in English and Mandarin. The resource is intended to help healthcare professionals, medical researchers and the public, bringing together content from Elsevier’s medical journals, textbooks and clinical experts, alongside resources from other information providers and
Establish an ATMP coordination body at EU/EEA level Ensure authorities in regions of treatment are compensated for costs of treating patients from other regions Encourage greater alignment within Europe on product value assessment activities The Alliance for Regenerative Medicine (ARM), the international advocacy organization representing the cell and gene therapy and broader advanced therapies sector,
A newly published study on @EClinicalMed by @CUHKofficial aims to formulate a composite model composed of clinical parameters and circulating markers in the prediction of curve progression. In adolescent idiopathic scoliosis (AIS), the continuous search for effective prognostication of significant curve progression at the initial clinical consultation to inform decision for timely treatment and to
Stanford data scientists have shown that figuring out a single number can help them find the most dangerous cancer cells. Biomedical data scientists at the Stanford University School of Medicine have shown that the number of genes a cell uses to make RNA is a reliable indicator of how developed the cell is, a finding that could
Researchers from KU Leuven and University Hospitals Leuven have managed to engineer living implants in the lab by mimicking how bone tissue is created in an embryo. The technology paves the way for bone-regenerating tissue implants created on an industrial scale using 3D bioprinting. The researchers expect the first living implants to be available to
The ISSCR is updating its Guidelines for Stem Cell Research and Clinical Translation to respond to recent scientific advances that include the use of pluripotent stem cell (PSC) to create models of early human embryo development (see Stem Cell Reports 14:1-6). As the science continues to advance, it raises important scientific, clinical, ethical, and societal issues for researchers,
Therapy shown to relieve extreme pain in mice. Now moving towards human trials. Human stem cells and “pain-killing neurons” have successfully relieved chronic pain in mice. The breakthrough method may be tested on human patients suffering untreatable pain within five years. Researchers at the University of Sydney have used human stem cells to make pain-killing
Identification of GPR108 as ‘lock’ for adeno-associated virus vector (AAV) is crucial to this emerging novel class of genetic medicine and may provide framework for developing more targeted gene therapies Researchers led by a team at Massachusetts Eye and Ear have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types–the most commonly
