Up to half of all people living with Alzheimer’s Disease in Ireland remain undiagnosed. A new blood test may have the potential to transform patient care, allowing for better diagnosis, earlier interventions and more targeted treatments Researchers at Trinity College, the Tallaght Institute of Memory and Cognition and St James’s Hospital, Dublin are exploring the
Called PAC-MANN, the test developed at OHSU could help save lives A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers. Researchers at Oregon Health & Science University have developed a test called PAC-MANN, the abbreviation for “protease activity-based assay using a magnetic nanosensor,”
A 3D-printed, bioresorbable heart valve promotes tissue regeneration, potentially eliminating the need for repeated surgeries for adult and pediatric heart patients. Every year, more than 5 million people in the U.S. are diagnosed with heart valve disease, but this condition has no effective long-term treatment. When a person’s heart valve is severely damaged by a birth defect,
Researchers at McMaster University have made a groundbreaking discovery in the field of hematology, providing an explanation for spontaneous and unusual bleeding episodes that continue to occur despite treatment with full-dose blood thinners. The discovery, published February 12, 2025 in The New England Journal of Medicine is expected to impact the way doctors test and treat patients
Analysis looked for—and did not find—examples where the process of generating CAR T cells caused malignancy Within a large group of more than 700 patients treated with CAR T cell therapy, researchers found no evidence that the therapy itself caused any type of secondary cancer in the modified T cells, according to new analysis reported
A team of physicists at Tampere University has developed a groundbreaking method for detecting congestive heart failure with greater ease and precision than previously thought possible. This multidisciplinary study, involving both cardiologists and computational physicists, builds on the team’s earlier breakthroughs, for example, in predicting the risk of sudden cardiac death. Researchers at Tampere University
GLP-1 medications tied to decreased risk of dementia, addiction; increased risk of kidney, pancreas and gastrointestinal problems Demand for weight-loss medications sold under brand names such as Ozempic and Wegovy continues to surge, with a recent study reporting one in eight Americans has taken or is currently using the drugs to treat diabetes, heart disease
One of the Largest Studies of its Kind Finds Early Intervention with Iron Delivered Intravenously During Pregnancy is a Safe and Effective Treatment for Anemia Anemia during pregnancy is a common occurrence and often due to iron deficiency. It is a global public health problem, affecting an estimated 37 percent of pregnant individuals, according to
Novel research in cells and mice models has provided insight into the mechanisms that regulate trogocytosis, a process during which immune cells can exchange membrane-bound proteins. The study showed that chimeric antigen receptor cells (so-called CAR-T cells) could transfer tumour antigen-specific receptors to recipient T cells, and in doing so equipped the latter cells with tumour-targeting
