Adding a personalised mRNA vaccine to plain remedy might supply new hope for pancreatic cancer sufferers, a small but promising study from Memorial Sloan Kettering Cancer Center. The study adopted 16 sufferers, together with Barbara Brigham, who joined the trial after a routine scan found her early-stage pancreatic cancer. Alongside surgical procedure and chemotherapy, sufferers
The use of semaglutide (Ozempic) was tied to a risk of nonarteritic anterior ischemic optic neuropathy (NAION) in adults with type 2 diabetes, according to a retrospective study. In this review of 37.1 million patients, the incidence rate of NAION among semaglutide users was 14.5 and 8.7 per 100,000 person-years using the sensitive and specific
A bone marrow transplant process co-developed by investigators at the Johns Hopkins Kimmel Cancer Center is safe and curative for adults with sickle cell disease, according to results of a trial completed at Johns Hopkins and about 20 additional cancer centers nationwide and in London. The treatment, available at multiple U.S. medical centers, is a viable and
Researchers from the University of Twente’s TechMed Centre and Radboud University Medical Centre removed blood clots using wireless magnetic robots. This innovation could revolutionise the treatment of life-threatening vascular diseases such as thrombosis. Cardiovascular diseases such as thrombosis are a major health problem worldwide. Worldwide, one in four people die each year from conditions caused
Researchers from the NIHR Moorfields Biomedical Research Centre and University College London have found that gene therapy improved visual acuity and preserved retinal structure in young children with AIPL1-associated severe retinal dystrophy. This is the first human trial of gene supplementation therapy targeting this condition. Retinal dystrophy caused by biallelic variants in the AIPL1 gene
An 18-year survivor of neuroblastoma, a solid childhood tumor that develops in immature nerve cells, is believed to represent the longest reported remission to date in a patient treated with chimeric antigen receptor (CAR) T cell therapy. The findings, published in Nature Medicine, describe several long-term survivors in a follow-up from a phase 1 clinical trial
GLP-1 medications initially were used to help people with diabetes improve their insulin resistance and hunger cravings. However, over the past few years, these medications have become popular due to their weight loss and weight management benefits. Outside of nutrition, physical activity and surgery, Dr. Saundra Nguyen, assistant professor of internal medicine at Baylor College of Medicine, explaining
A simple scoring system could revolutionise how doctors prevent heart attacks and strokes by identifying patients most likely to benefit from preventive medications, according to a new study. The breakthrough test, called the TRIPLE Score, (Thrombotic Reactivity Indicator using Platelet GPVI, CD36 [cluster of differentiation 36] Expression, and age) measures specific proteins on blood platelets
The American Academy of Neurology (AAN) has developed a new systematic review to summarize for neurologists and other clinicians the evidence for epidural steroid injections and whether they reduce pain and disability for people with certain kinds of chronic back pain. The systematic review is published on February 12, 2025, online in Neurology®. It updates
Blood thinners prescribed after blood clots in leg or lung initially increase the risk of bleeding, especially in women and elderly. But over time, this risk decreases and gender and age differences fade, a University of Gothenburg study shows. The aim of the study, published in the Journal of Internal Medicine, was to investigate the
