New options make care faster, safer, and more accessible At a glance: Tuberculosis remains one of the top infectious disease killers worldwide, a challenge amplified by drug-resistant forms of the disease. Now, in a major step forward, an international clinical trial has found three new safe and effective drug regimens for tuberculosis that is resistant to
New research, with the caveat of a relatively short follow-up, adds to encouraging data showing an overall low risk of the development of thyroid cancer associated with glucagon-like peptide 1 receptor agonist (GLP-1 RA) treatment. However, a notably increased rate of thyroid cancer detections limited only to the first year after drug initiation — but
First Drug Approved in New Class of Non-Opioid Pain Medicines; Agency Continues to Take Steps to Support New Approaches for Pain Management the U.S. Food and Drug Administration approved Journavx (suzetrigine) 50 milligram oral tablets, a first-in-class non-opioid analgesic, to treat moderate to severe acute pain in adults. Journavx reduces pain by targeting a pain-signaling
The heart patch is produced from induced pluripotent stem cells derived heart muscle cells in a collagen hydrogel. Results from rhesus macaques provide solid ground for a first-in-human investigation of heart repair with stem cell-derived engineered heart muscle. The study is a milestone for the clinical application of the ‘heart patch’ as an innovative treatment
EPFL researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for future fracture prevention therapies in osteoporosis patients. Osteoporosis is a disease in which bone resorbs faster than it is formed, gradually weakening its structure over time and leading
Research from the University of Colorado Anschutz Medical Campus reveals drug could potentially help repair vision in those with multiple sclerosis (MS) and other neurological conditions Researchers at the University of Colorado Anschutz Medical Campus have found a promising drug candidate that could help restore vision in individuals with multiple sclerosis (MS) and other neurological conditions that
Women in early menopause treated with zoledronate in just two infusions, 5 years apart, show a significantly reduced risk of sustaining a vertebral fracture and better maintenance of bone mineral density (BMD) over a 10-year period than those receiving just one or no infusions over the period, suggesting the infrequent, early dosing to be a
Megakaryocytes (MKs) are traditionally recognized for their crucial role in platelet production, which is vital for hemostasis and coagulation. However, recent studies have illuminated their far-reaching involvement in immune responses within both physiological and pathological environments. Advances in immunology and cellular biology have revealed the significant immunomodulatory functions of MKs, changing our understanding from their
Every 40 seconds, someone in the United States has a stroke. For survivors of the most common type of stroke, called an ischemic stroke, only about 5 percent fully recover. Most others suffer from long-term problems, including weakness, chronic pain, or epilepsy. Now, scientists at Gladstone Institutes and the regenerative medicine company SanBio have shown
Study identifies a novel mechanism driving osteosarcoma and provides insights to help predict patient outcomes Summary Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people
