The host protein fibrinogen has been found to interact with the N-terminal domain (NTD) of the spike protein in SARS-CoV-2 as an immune evasion strategy adopted by the virus to outsmart the NTD targeted neutralizing antibodies. The journey of the COVID-19 virus, which emerged in early 2019, has been nothing short of remarkable as it
A new consensus paper, published by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), the International Osteoporosis Foundation (IOF), and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC), provides an updated evaluation of reference bone turnover markers (BTMs) and newer markers in the diagnosis and management
Maintaining a healthy diet rich in plant-based foods, with low to moderate intake of healthy animal-based foods and lower intake of ultra-processed foods, was linked to a higher likelihood of healthy aging—defined as reaching age 70 free of major chronic diseases and with cognitive, physical, and mental health maintained, according to a new study by
After the COVID-19 pandemic, the incidence rate of postural orthostatic tachycardia syndrome increased significantly, according to new data published in the European Heart Journal – Quality of Care and Clinical Outcomes. “Postural orthostatic tachycardia syndrome (POTS) is a chronic condition characterized by an abnormal increase in heart rate upon standing, often accompanied by symptoms such as dizziness, lightheadedness, fatigue
Researchers have developed a smartphone app that uses machine learning to accurately determine body composition – which is linked to a higher risk of heart disease, stroke and related conditions – from photographs. The researchers, from the University of Cambridge, developed the smartphone app called 3D BodyShape, which is currently a research prototype and will
Researchers showed that older patients with heart failure who exercised regularly before hospitalization had better physical function and lower mortality Exercise is widely recognized as beneficial for patients with heart failure, with current guidelines relying on introducing exercise after heart failure diagnosis. This leaves a noticeable lack of research on the impact of habitual physical
A t-shirt that monitors a patient’s vitals after urological surgery for cancer could help people return from hospital sooner to recover at home. The device, worn for around two weeks under clothes for three-hour windows each day, enabled patients to feel safer and more reassured than a control group in a pilot study of 70
Scientists at Neurorestore (EPFL/CHUV/UNIL) have developed an approach that combines rehabilitation robotics with spinal cord stimulation to restore movement in people with spinal cord injuries. The technology enhances rehabilitation and enables activities like cycling and walking outdoors. Spinal cord injuries are life-altering, often leaving individuals with severe mobility impairments. While rehabilitation robotics—devices that guide movement
Newly developed artificial intelligence can account for how the brain changes as we learn, enabling a person with paralysis to move objects Researchers at UC San Francisco have enabled a man who is paralyzed to control a robotic arm that receives signals from his brain via a computer. He was able to grasp, move and
Key Takeaways The FDA has approved tenecteplase (TNKase; Genentech) for the treatment of acute ischemic stroke (AIS) in adults, according to a Genentech announcement.1 The thrombolytic medicine is an intravenous (IV) tissue plasminogen activator that is clot-dissolving, administered as a single 5-second IV bolus. The company noted that it will be providing a 25-mg vial configuration
