Archives: 2022-03-03

COVID-19 infections increase risk of heart conditions up to a year later

Cardiovascular care essential part of post-infection care An analysis of federal health data indicates that people who have had COVID-19 are at increased risk of developing cardiovascular complications within the first month to a year after infection, according to researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis

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CAR-based therapies an opportunity for immuno-medicine beyond cancer: a review published on Nature Metabolism

CAR T therapy has had enormous impact in some areas of oncology, and notable efforts are underway to extend the success to additional forms of cancer. However, the use of engineered T cells may be evenmore attractive for disorders other than cancer for several reasons. This review analyses different opportunities and future directions. First, for

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Connecting science to medicine: tendon-like tissue created from human stem cells

Researchers from Tokyo Medical and Dental (TMDU) develop artificial tendons in vitro from human stem cells that could fix common tendon injuries such as Achilles tendon rupture.  Tendons are tissues that connect muscles to bones and are important for movement and locomotion. Injuries to tendons are quite common, with millions of people – particularly athletes

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Gene Therapy for Thalassemia Ends Need for Transfusions in Young Children

Phase 3 clinical trial included children younger than 12 years Over 90 percent of patients with transfusion-dependent thalassemia, an inherited blood disorder, no longer needed monthly blood transfusions years after receiving gene therapy, according to an international Phase 3 clinical trial that for the first time included children younger than 12 years of age. Twenty-two patients

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A new study shows MIS-C is rare among teens COVID-19 vaccinated

COVID-19 vaccines are unlikely to trigger a rare inflammatory condition linked to coronavirus infection in children, according to an analysis of U.S. government data published Tuesday. The condition, formally known as multisystem inflammatory syndrome in children, involves fever plus symptoms affecting at least two organs and often includes stomach pain, skin rash or bloodshot eyes. It’s

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Mesenchymal stem cell‑based treatments for COVID‑19: an updated review

This review describes the origins, pathogenesis, and clinical features of COVID-19 and the potential uses of mesenchymal stem cells (MSCs) in therapeutic treatments for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients. MSCs have previously been shown to have positive effects in the treatment of lung diseases, such as acute lung injury, idiopathic pulmonary fibrosis,

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Vertebral body tethering: Another option for treating scoliosis in children

Fusion surgery has been the long-standing treatment for people with scoliosis – a side-to-side curve of the spine. But other options have become available — including vertebral body tethering for children with scoliosis. “Vertebral tethering is a new tool in the tool kit for the treatment of scoliosis,” says A. Noelle Larson, M.D., a pediatric orthopedic surgeon at Mayo

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Foreseeing the future of European medicine

Experts say careful application of advanced tech could usher in a golden age of healthcare New technologies could enable medicine to progress in leaps and bounds, but only with the right regulatory and ethical frameworks. That was one of the messages from panelists discussing the future of medicine at the Science|Business conference Horizon Europe: The first assessment as

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Advances in CAR-T Cell Genetic Engineering Strategies to Overcome Hurdles in Solid Tumors Treatment: a review published on Frontiers

In this review, it’s provided an overview of the major mechanisms used by tumor cells to evade immune defenses and are critically exposed the most optimistic engineering strategies to make CAR-T cell therapy a solid option for solid tumors. CAR-T cell based cell therapy is a moving field, which showed impressive results in hematopoietic cancer

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Gene Therapies Developers slowly emerge from a pandemic: a new ebook published by BioProcess Insider

This eBook gauges shifting expectations for the gene therapy industry amid the COVID-related uncertainties and clinical setbacks of the past couple years. BioProcess Insider founding editor Dan Stanton reports on the January 2022 Phacilitate Advanced Therapies Week event, specifically a standing presentation on the 10 most important industry drivers from the past year. Since 2017, advancements in

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