Archives: 2022-01-20

Immunomodulatory effects of mesenchymal stem cells in peripheral nerve injury: a review

Peripheral nerve injury (PNI) refers to varying degrees of trauma to peripheral nerve stems or branches. PNIaccounts for 1.5–4.0% of global trauma cases annually and is one of the most challenging health issues at present. Nerve regeneration is a complicated cellular process involving infammation, neurotrophic factors, neurotransmitters, adhesion, the formation of axons and growth cones,

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Placebo Effect Accounts for More Than Two-Thirds of COVID-19 Vaccine Adverse Events, Researchers Find

One-Third of Clinical Trial Participants Who Received No Vaccine Reported Systemic Adverse Advents Like Headache and Fatigue The placebo effect is the well-known phenomenon of a person’s physical or mental health improving after taking a treatment with no pharmacological therapeutic benefit – a sugar pill, or a syringe full of saline, for example. While the

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Epilepsy Research Boosts Case for New Gene Therapy

Research from the School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a severe form of epilepsy, and potentially prolong survival for people with the condition. The gene therapy, developed by Stoke Therapeutics, is now in clinical trials. Because most Dravet syndrome cases are caused by a mutation in the SCN1A gene, resulting in

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SARS-CoV-2 variants of concern and variants under investigation in England: technical briefing published by UK Health Security Agency

This report has been published to share the detailed variant surveillance analyses which contribute to the variant risk assessments and designation of new variants of concern (VOC) and variants under investigation (VUI). This specialist technical briefing contains early data and analysis on emerging variants and findings have a high level of uncertainty. SARS-CoV-2 Routine variant

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Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain

Survivors of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection frequently experience lingering neurological symptoms, including impairment in attention, concentration, speed of information processing and memory. This long-COVID cognitive syndrome shares many features with the syndrome of cancer therapy-related cognitive impairment (CRCI). Neuroinflammation, particularly microglial reactivity and consequent dysregulation of hippocampal neurogenesis and oligodendrocyte lineage cells,

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Association between vaccination status and reported incidence of post-acute long-COVID-19 symptoms in Israel: double dose Pfizer-BioNTech vaccination may have a protective effect.

An emerging and complex health problem that remains poorly characterized and understood is long coronavirus disease 2019 (Long COVID). The rapid outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic. Long COVID is a post-infection condition in which individuals do not recover completely for

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