Archives: 2021-12-05

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19 and some vaccines complications

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field. Researchers are working to find effective vaccines and therapies, as well as understand the long-term effects of the infection. While the vaccines have been critical in pandemic control, researchers are still

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High-titre convalescent plasma therapy not effective against severe COVID-19 pneumonia: results of Italian TSUNAMI randomized clinical trial

1. Amongst patients with severe COVID-19 pneumonia, there was no difference in 30-day all-cause mortality, ventilation or cure in patients receiving convalescent plasma (CP) plus standard therapy versus standard therapy alone. 2. CP treatment was associated with more adverse events, including 5 instances of respiratory failure requiring treatment interruption. Patients who have recovered from SARS-CoV-2

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New study of Karolinska Institute and Helsinki University shows how digital and molecular data can be integrated to prevent ill health

With the development of sensors, apps and other digital alternatives for health monitoring, the individual’s opportunities to work proactively for better health and well-being increase. At the same time, the measurement of many different biomolecular variables (so-called multiomics) enables a deep and comprehensive profiling of human biology. – Instead of focusing on the treatment of the

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A detailed study by Max Planck Institute shows the maximum risks of being infected by SARS-CoV-2 for different scenarios with and without masks

Three metres are not enough to ensure protection. Even at that distance, it takes less than five minutes for an unvaccinated person standing in the breath of a person with Covid-19 to become infected with almost 100 percent certainty. That’s the bad news. The good news is that if both are wearing well-fitting medical or,

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Scientists of Arizona State University discover potential mechanism behind rare blood clots linked to adenovirus COVID-19 vaccines (VITT)

A cloud of platelet factor 4 proteins interacts with the electrostatic surface of the Oxford vaccine, as seen through the computational microscope.  An international team of scientists believe they may have found a molecular mechanism behind the extremely rare blood clots linked to adenovirus COVID-19 vaccines. “The mechanism which results in this condition, termed vaccine-induced

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Safety and immunogenicity of booster COVID-19 vaccine following two previous doses of AstraZeneca or Pfizer-BioNTech in the UK

Six different COVID-19 boosters are safe and provoke strong immune responses in people who have previously received a two-dose course of ChAdOx1-nCov19 (Oxford–AstraZeneca [ChAd]) or BNT162b2 (Pfizer-BioNTech [BNT]), according to the first randomised trial of boosters given after two doses of either vaccine, published in The Lancet. ChAd has now been deployed in more than 180

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Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic. A comment on The Lancet by researchers of Centre for the AIDS Programme of Research in South Africa

A new comment on Omicron SARS-CoV-2 variant has been published on The Lancet by South African researchers of Centre for the AIDS Programme of Research in Durban South Africa. The Authors highlight that the first sequenced omicron case was reported from Botswana on Nov 11, 2021, and a few days lateranother sequenced case was reported

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Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells using the CompacT SelecT (CTST) platform

The CompacT SelecT (CTST) platform is a modular robotic system that integrates a full range of cell culture proceduresunder sterile conditions that mimic the manual cell culture process. These procedures include automated handling of different cell culture vessels, pipetting large and small volumes at adjustable speeds, cell counting, cell viability analysis, cell density assessment, microscopic

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Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa 2021-12-01: new paper published in medRxiv

Objective of the paper is to examine whether SARS-CoV-2 reinfection risk has changed through time in South Africa, in the context of the emergence of the Beta, Delta, and Omicron variants A retrospective analysis of routine epidemiological surveillance data Setting Line list data on SARS-CoV-2 with specimen receipt dates between 04 March 2020 and 27

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