Archives: 2021-03-12

UK Royal College of Physicians calls for urgent measures to protect and safeguard medical workforce involved in fight against Covid-19

In an article published in The Lancet, RCP president Professor Andrew Goddard and RCP Global vice president Dr Mumtaz Patel call for system-wide support to protect clinicians from harm. The COVID-19 pandemic has placed huge demands on global health systems which are testing doctors and health-care workers to the limits of their professional competence and taking

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A new study on BMJ shows an increase in deaths from 2.5 to 4.1 per 1000 detected cases in SARS-CoV-2 B.1.1.7 variant

A highly infectious variant of COVID-19 that has spread around the world since it was first discovered in Britain late last year is between 30% and 100% more deadly than previous dominant variants, researchers said on Wednesday. In a study that compared death rates among people in Britain infected with the new SARS-CoV-2 variant known

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The challenges of CAR T-cell therapy for pediatric B-ALL. RESTORE launched Fragments of Life: A success in the frontier of medicine becomes a video game.

Sara Ghorashian, PhD, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK, outlines the challenges associated with CAR T-cell therapy for pediatric B-cell acute lymphoblastic leukemia (ALL). Discovering the best treatment phasing with other immunotherapies, such as blinatumomab and inotuzumab, improving the toxicity profile, and CAR T-cell persistence are some of the remaining

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NIH/NIDDK Researchers propose that masking induced humidity, hydrating the respiratory tract, may lessen severity of COVID-19

Masks help protect the people wearing them from getting or spreading SARS-CoV-2, the virus that causes COVID-19, but now researchers have added evidence for yet another potential benefit for wearers: The humidity created inside the mask may help combat respiratory diseases such as COVID-19. Masks help protect the people wearing them from getting or spreading

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Neurologic Involvement in Children and Adolescents Hospitalized in the US for COVID-19 or MISC

Most are transient, but some develop into life-threatening disorders Neurologic symptoms occurred frequently in children and adolescents hospitalized with COVID-19, a large case series of pediatric patients in the U.S. showed. Of 1,695 people 21 or younger hospitalized for acute COVID-19 or multisystem inflammatory syndrome in children (MIS-C), more than one in five (22%) had

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New Google-Backed Database Tracks Details on SARS-CoV-2 and Variants Cases Worldwide

A group of US and European epidemiologists on Tuesday launched an open international database that presents granular information on 5 million anonymized COVID-19 cases from more than 100 countries. Each case record in the database, which is housed at Global.health, contains up to 40 variables, including information such as the patient’s demographics and location, the date

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An Israel study on in health-care workers at the Sheba Medical Centre vaccinated with BNT162b2 vaccine shows substantial early reductions in Covid-19 infections following firts dose administration

There has been some research that suggests the Pfizer/BioNTech vaccine provides some protection after one dose. Researchers at Israel’s largest hospital looked at what happened after 7,000 staff got vaccinated with the first dose of the Pfizer/BioNTech vaccine. By the second to fourth week after they got the first shot, rates of symptomatic infection were down by

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Can it work a single-dose Oxford–AstraZeneca COVID-19 vaccine followed by a 12-week booster in a wide vaccination strategy ?

Vaccines to prevent COVID-19 infection are crucial for an effective global pandemic response. In The Lancet, Merryn Voysey and colleagues report the updated primary efficacy results for the Oxford–AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine from three single-blind, randomised controlled trials in the UK and Brazil and one double-blind study in South Africa. A subsequent report of

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Transmission, reinfection and vaccine efficacy update for major SARS-CoV-2 variants B.1.1.7 (UK), B.1.3.5.1 (South Africa) and P1 (Brazil).

The topics was discussed in a recent webinar that the Massachusetts Consortium on Pathogen Readiness (MassCPR) held to “demystify” the new viral variants. Each consists of several mutations. Will the variants fuel “a novel stage of contagion, COVID 2.0?” opened George Daley, MD, PhD, dean of Harvard Medical School. “What has been unsettling is how many times mutations

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