Moderna said its COVID-19 vaccine is 96 percent effective among youths aged 12 to 17, according to the results of its first clinical trials. Two-thirds of the 3,235 participants in trials in the United States received the vaccine and one-third were given a placebo. The study “showed vaccine efficacy against COVID-19 of 96%; mRNA-1273 was generally well
Norwegian and Danish researchers published a register study in BMJ of over 281,000 people who have received the AstraZeneca vaccine. – The study confirms previous findings from OUS and internationally. The registry study finds 11 additional cases of venous thrombosis among 100,000 vaccinated. The article that follows people who have received the AstraZeneca vaccine in
A new study is drawing the most detailed picture yet of SARS-CoV-2 infection in the lung, revealing mechanisms that result in lethal COVID-19, and may explain long-term complications and show how COVID-19 differs from other infectious diseases. Led by researchers at Columbia University Vagelos College of Physicians and Surgeons and Herbert Irving Comprehensive Cancer Center, the study found
In a major shot in the arm for the Pfizer-BioNTech COVID-19 vaccine, researchers have reported in two studies that it is highly effective in protecting against severe COVID-19 infections caused by the variants first reported in the UK and South Africa. In a study published in the New England Journal of Medicine on May 5, researchers analysed
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is highly contagious and causes lymphocytopenia, but the underlying mechanisms are poorly understood. In this paper published on Nature fresearchers of Laboratory of Cell Engineering, Institute of Biotechnology, Beijing, China demonstrate that heterotypic cell-in-cell structures with lymphocytes inside multinucleate syncytia are prevalent in the lung tissues
A study published in July 2020 hypothesized a link between the presence of bradykinin, a well-known peptide, and severe cases of COVID-19. Vardan Karamyan, Ph.D., an associate professor and vice chair for the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy Department of Pharmaceutical Sciences, had not previously conducted or
In the search for treatments for COVID-19, many researchers are focusing their attention on a specific protein that allows the virus to infect human cells. This protein, which cells carry on their surface, is called angiotensin converting enzyme 2 (ACE2) and provides the entry point for the coronavirus to enter cells. ACE2 is present in
COVID-19 is associated with a high incidence of thrombotic complications, which can be explained by the complex and unique interplay between coronaviruses and endothelial cells, the local and systemic inflammatory response, and the coagulation system. Empirically, an intensified dose of thrombosis prophylaxis is being used in patients admitted to hospital with COVID-19 and several guidelines
Clinical trials have shown the COVID-19 vaccines now being administered around the country are highly effective in protecting fully vaccinated individuals from the coronavirus SARS-CoV-2. But will they continue to offer sufficient protection as the frequency of more transmissible and, in some cases, deadly emerging variants rise? More study and time is needed to fully
Spinal fusion is frequently performed to restore spinal stability in patients with spinal diseases, such as spinal stenosis, vertebral fractures, progressive deformities, and instability. In the past two decades, there has been marked increase in the number of people over 65 years in age who have needed spinal fusion surgery. While autogenous bone grafts have
