British doctors have identified two factors — very low platelet counts and brain bleeds — which they say dramatically increase the likelihood of a patient dying following the very rare but devastating side effect of vaccine-induced immune thrombocytopenia and thrombosis (VITT) after the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccine. However, they believe that the surge in the VITT side
Symptoms for early COVID-19 infection differ among age groups and between men and women, new research has found. These differences are most notable between younger age groups (16-59 years) compared to older age groups (60->80 years), and men have different symptoms compared to women in the early stages of COVID-19 infection. The paper, published today in
The Centers for Disease Control and Prevention recommends that fully vaccinated people once again wear a face mask in public in areas with substantial or high transmission of COVID-19. The Centers for Disease Control and Prevention (CDC) recommends that fully vaccinated people once again wear a face mask inside in public in areas with substantial
More than 1.5 million children around the world have lost a parent, grandparent, or other caregiver to COVID-19, according to the first global study of its kind. In the study, published yesterday in The Lancet, a team led by US Centers for Disease Control and Prevention (CDC) scientists used death and fertility data to model minimum estimated
Patients who are acutely unwell with suspected vaccine induced immune thrombocytopenia and thrombosis (VITT) should be referred immediately to the emergency department, says new rapid guidance from the National Institute for Health and Care Excellence (NICE). National Institute for Health and Care Excellence. Covid-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis (VITT) NICE guideline [NG200].
The Coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), becomes a global threat to humanity. In severe COVID-19 patients, excessive proinflammatory responses and impaired host immune system are observed which could result in the progression of acute respiratory distress syndrome (ARDS) and even death. In-depth investigation of SARS-CoV-2 infected
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with thrombotic complications in adults, but the incidence of COVID-19-related thrombosis in children and adolescents is unclear. Most children with acute COVID-19 have mild disease, but coagulopathy has been associated with multisystem inflammatory syndrome in children (MIS-C), a postinfectious complication.
The full two-dose regimen of Pfizer’s COVID-19 vaccine was 78 percent effective in preventing infection among pregnant women, according to a real-world Israeli study published July 12 in JAMA. Researchers analyzed data on 7,530 pregnant women who received their first dose of Pfizer’s vaccine between Dec. 19 and Feb. 28 in Israel. The women were matched
Is there enough evidence to show Biogen’s new Alzheimer’s drug Aduhelm provides a benefit to patients, physicians and society beyond the current standard care? The answer from a group of ICER experts, perhaps unsurprisingly, was “no.” During a daylong meeting Thursday that featured debate over the drug’s cost and more, experts voted 15 to 0 that
EMA’s safety committee, PRAC, has concluded that there is no evidence linking the viral vector in Zynteglo to a blood cancer known as acute myeloid leukemia (AML). The European Medicines Agency’s (EMA’s) Pharmacovigilance Risk Assessment Committee (PRAC) has concluded that there is no evidence linking the viral vector in Zynteglo to a blood cancer known
