Archives: 2020-02-06

Experts offer first US nCoV clinical guidance. Younger people are getting infected, but they get the relatively milder disease

Both the Journal of the American Medical Association (JAMA) and the Centers for Disease Control and Prevention’s (CDC’s) Morbidity and Mortality Weekly Report (MMWR) published initial clinical guidelines, which aim to help US healthcare providers identify and correctly handle suspected cases involving the novel coronavirus (2019-nCoV). 2019-nCoV was first identified in Wuhan, China, the country that continues to report

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Remdesivir and chloroquine effectively inhibit the recently emerged novel #coronavirus (2019-nCoV) in vitro. Letter to the editor of Nature Cell Research

The Wuhan Institute of Virology of the China Academy of Sciences, based in the city where the outbreak is believed to have originated, said in a statement on Tuesday it applied to patent the use of Remdesivir, an antiviral drug developed by Gilead (GILD.O), to treat the virus. A study published in the New England

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£20m announced to fund vaccines for coronavirus and other infectious diseases by UK Government to CEPI

The UK Government has today pledged £20 million to develop new vaccines to combat the world’s deadliest diseases, amid concerns over the ongoing novel coronavirus outbreak in China. When visiting the Public Health England’s Porton Down laboratory last week, Health Secretary Matt Hancock announced the UK will ramp up efforts to fund ground-breaking research into

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Rice University bioengineers 3D-print grooved implants to seed multiple layers of tissue

Grooves hold promise for sophisticated healing The Rice University team led by Antonios Mikos says otherwise with its development of a groovy method to seed sophisticated, 3D-printed tissue-engineering scaffolds with living cells to help heal injuries. The researchers are literally carving grooves into plastic threads used to build the scaffolds. The grooves are then seeded with cells

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Blocking pro-fibrosis signaling pathway may improve immunotherapy of metastatic breast cancer

A Massachusetts General Hospital (MGH) research team has found that the overgrowth of connective called fibrosis may block the effectiveness of immunotherapies against metastatic breast cancer. Their report published in PNAS also finds that plerixafor, a drug approved to mobilize blood system stem cells in the treatment of lymphoma and multiple myeloma patients, can reduce fibrosis in

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#Coronavirus will likely become a pandemic, warns ex-FDA commissioner Scott Gottlieb in interview to CNBC

“We will have outbreaks here in the United States,” former U.S. Food and Drug Administration commissioner Scott Gottlieb said of the coronavirus. “Now, a small outbreak doesn’t need to become a large outbreak, a large outbreak doesn’t need to become an epidemic here in the United States. There’s things we can do, but we’re going

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A Fundamental Discovery About How Gene Activity Is Regulated

Researchers at Johns Hopkins Bloomberg School of Public Health have discovered a fundamental mechanism that regulates gene activity in cells. The newly discovered mechanism targets RNA, or ribonucleic acid, a close cousin of DNA that plays an important role in cellular activity. The discovery, detailed in a paper published February 3 in the journal Molecular Cell, is a

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