Immunotherapy has unleashed a revolution in care for some cancer patients. But most immunotherapies help only a small subset of patients, meaning doctors often have to resort to a trial-and-error process to determine who might actually benefit from the novel treatments. Now, scientists have developed a new metric they believe can help predict whether patients will respond
Chimeric antigen receptor (CAR) T-cell therapy may keep advanced blood cancers at bay, but it can’t keep the wolf from the door, warn experts on healthcare policy and financing. For all the talk about the steep costs of CAR T-cell therapy and how to pay for it, comparatively little attention has been paid to the
Source Reuters A 70-year-old man in China’s Hubei Province was infected with coronavirus but did not show symptoms until 27 days later, the local government said on Saturday, meaning the virus’ incubation period could be much longer than the presumed 14 days. A longer incubation period could complicate efforts to contain spread of the epidemic
Researchers from The University of Texas at Austin and the National Institutes of Health have made a critical breakthrough toward developing a vaccine for the 2019 novel coronavirus by creating the first 3D atomic scale map of the part of the virus that attaches to and infects human cells. Mapping this part, called the spike
Gene-infused nanoparticles used for combating disease work better when they include plant-based relatives of cholesterol, new research shows. That’s because the shape and structure of the phytosterols help the genes get where they need to be inside cells. The findings by Oregon State University researchers, published today in Nature Communications, are important because many illnesses that
If approved, 1st Gene Therapy in U.S. for the Treatment of Any Type of Hemophilia BioMarin Pharmaceutical Inc. (Nasdaq: BMRN) today announced that the U.S. Food and Drug Administration (FDA) has accepted for Priority Review the Biologics License Application (BLA) to the FDA for its investigational AAV5 gene therapy, valoctocogene roxaparvovec, for adults with hemophilia
Neel Anand, MD, serves as professor of orthopedic surgery and director of spine trauma at the Cedars-Sinai Spine Center in Los Angeles. Dr. Anand has dedicated his practice to the advancement of minimally invasive spine surgery and served as principal investigator in several FDA clinical trials. Here, Dr. Anand discusses the hype around stem cells and
Egypt, Algeria and Republic of South Africa are the African countries most at risk for coronavirus COVID-19 importation in the continent, due to high air traffic with the contaminated Chinese provinces. But these countries are also among the best equipped on the continent to quickly detect and deal with new cases. In other African countries,
Industry leaders, patient advocates, researchers unite to maximize the incredible potential of transformative gene therapies The Institute for Gene Therapies (IGT) launched today with a focus on advocating for a modernize the U.S. regulatory and reimbursement framework so that gene therapies can deliver their significant potential to patients. IGT will educate stakeholders across the healthcare
By carefully harvesting tiny samples of olfactory cleft mucosal tissue and conducting single-cell analysis, a collaborative team led by University of Miami Miller School of Medicine researchers has found compelling evidence to support olfactory neurogenesis, the ability to regrow olfactory neurons to the brain. “For decades, medical researchers have wondered whether or not neurogenesis was
