RESTORE, a pan-European initiative that aims to accelerate the availability of Advanced Therapies for the benefit of patients and society, is working on a video game to raise awareness of the field of Advanced Therapies. One room, 60 photographs, a whole life. Ready to relive Ella’s story? Available within the next few weeks for free
Coronavirus disease 2019 (COVID-19) is associated with a high disease burden with 10% of confirmed cases progressing towards critical illness. Nevertheless, the disease course and predictors of mortality in critically ill patients are poorly understood. Following the critical developments in ICUs in regions experiencing early inception of the pandemic, the European-based, international RIsk Stratification in
The novel coronavirus pneumonia COVID-19 caused by SARS-CoV-2 infection could lead to a serious of clinical symptoms and severe illness, including acute respiratory distress syndrome (ARDS) and fatalorgan failure. The authors report the fundamental pathological investigation in the lungs and other organs of fatal cases after the autopsy and pathological investigations of specimens performed on
A team of University of Pavia, Italy presents on Lancet the case of 16-year-old boy admitted to emergency department, complaining of intense chest pain started 1 h earlier. The day before he had a fever of 38·3°C thatdecreased after 100 mg of nimesulide. He reported no other symptoms, no medical history, and no contact with
Researchers of Harvard Medical School, Boston have devised a way to decontaminate N95 respirators using household supplies: glass containers, mesh from produce bags, a rubber band, and a microwave. The paper by Zulauf KE, Green AB, Nguyen Ba AN, Jagdish T, Reif D, Seeley R, Dale A, Kirby JE has been published on mBio 11:e00997-20.
University of Oxford’s RECOVERY trial published its much anticipated preprint paper on the drug’s effect on Covid-19. The paper states that the drug cuts deaths in ventilated patients by one third and deaths in other admitted patients receiving oxygen by only one fifth. The headline findings of the trial were reported by the investigators on 16
Mayo Clinic researchers and collaborators have found investigational convalescent plasma to be safe following transfusion in a diverse group of 20,000 patients. The findings — from the U.S. Food and Drug Administration’s Expanded Access Program for COVID-19 — are reported in Mayo Clinic Proceedings. The safety report assessed the seven days following transfusion for hospitalized patients between April
Many people who contract COVID-19 have only a mild illness, or sometimes no symptoms at all. But others develop respiratory failure that requires oxygen support or even a ventilator to help them recover [1]. It’s clear that this happens more often in men than in women, as well as in people who are older or
The host immune system produces a variety of regulatory molecules, including interferons (IFNs), during a response to viral infection. Although previously considered beneficial, these proteins may actually cause life-threatening inflammation, according to an article published in Science on June 11. IFNs are a group of signaling proteins that are made and released by host cells in response
A new paper published on JAMA by Peter W. Marks and Stephen Hahn of FDA The products administered by clinics under the broad rubric of regenerative medicine include those derived from individuals’ own bone marrow or fat, those derived from birthing tissues such as placenta or cord blood obtained from a donor unrelated to the
