Archives: 2020-08-25

PIER MARIA FORNASARI
2020-08-25

Mayo Clinic Driven Expanded Access Program for Convalescent Plasma discontinues enrollment as FDA authorizes its emergency use

The Food and Drug Administration (FDA) authorized emergency use of convalescent plasma and the national Expanded Access Program (EAP) for convalescent plasma led by Mayo Clinic announced its intention to discontinue enrollment. The five-month program served 2,780 hospital and acute care facilities, with nearly 14,000 physicians enrolling 101,000 patients and reports of 71,000 infused so far. Eligible patients who

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PIER MARIA FORNASARI
2020-08-25

Kidney involvement by SARS-CoV-2 increases the risk of mortality and acute kidney failure.

The research presented early in the course of Corona pandemic found that Covid-19 not as initially suspected a classic viral lung disease. Rather, the whole body is affected . A team from the University Hospital Hamburg-Eppendorf (UKE) has now proven that the new coronavirus  SARS-CoV-2 can also multiply in the kidneys .  The novel corona virus can also multiply outside of the lungs, for example in the kidneys. Researchers at the University Medical Center

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PIER MARIA FORNASARI
2020-08-24

Not only antibodies: the role of B cells and T cells in mediating immunity to COVID-19

Recent reports that antibodies to SARS-CoV-2 are not maintained in the serum following recovery from the virus have caused alarm. However, the absence of specific antibodies in the serum does not necessarily mean an absence of immune memory. University of Bergen researchers have just published a paper on Nature Reviews Immunology. Immunity after infection with

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PIER MARIA FORNASARI
2020-08-24

FDA Covid-19 Convalescent Plasma Emergency Use Authorisation: Truth beyond Fictions

Source FDA Yesterday 08/23/2020 FDA has issued guidance to provide recommendations to health care providers and investigators on the administration and study of investigational convalescent plasma collected from individuals who have recovered from COVID-19 (COVID-19 convalescent plasma) during the public health emergency. The guidance provides recommendations on the following: pathways for use of investigational COVID-19 convalescent plasma

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PIER MARIA FORNASARI
2020-08-23

Risk of stroke in hospitalized SARS-CoV-2 infected patients. Results of a multinational study

There is an increased attention to stroke following SARS-CoV-2. The goal of this study was to better depict the short-term risk of stroke and its associated factors among SARS-CoV-2 hospitalized patients. This multicentre, multinational observational study includes hospitalized SARS-CoV-2 patients from North and South America (United States, Canada, and Brazil), Europe (Greece, Italy, Finland, and

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PIER MARIA FORNASARI
2020-08-22

An uncontrolled and placebo group lacking study on 35.000 patients suggests convalescent plasma shows a 3% reduced mortality in Covid-19 patients.

Infusing hospitalized Covid-19 patients with blood plasma from people who recovered from the disease appeared to show a benefit in a nationwide study, but the study’s lack of a placebo group left several experts struggling to interpret the data. The study, which enrolled more than 35,000 patients, found that quickly administering so-called convalescent plasma had

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PIER MARIA FORNASARI
2020-08-21

Shifting public health messaging about face coverings could improve uptake

Face coverings need to be grounded in the social and cultural realities of affected communities, say researchers. Encouraging the public to see face masks as a social practice, which they can use to express their cultural background or their personality, could encourage more people to use them regularly, say researchers writing in The BMJ today. Helene-Mari van

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PIER MARIA FORNASARI
2020-08-21

Triad of molecules could predict severity of COVID-19

In a new study, published in Nature Medicine, researchers at the Francis Crick Institute, King’s College London and Guy’s and St Thomas’ NHS Foundation Trust, have found a common immune signature in the blood of patients with COVID-19, which could be used to predict how severely ill a patient will become, thereby aiding patient management.  The team analysed blood samples

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