July 2020 – Page 2 – REGENHEALTHSOLUTIONS (RHS)

PIER MARIA FORNASARI
2020-07-23

High-dose glucocorticoids and IL-6 receptor inhibition reduce COVID-19-associated cytokine storm mortality

The Annals of the Rheumatic Diseases, the journal of the European League Against Rheumatism, EULAR, has published findings of an observational study on the treatment of patients with COVID-19-associated Cytokine storm syndrome (CSS). The study demonstrates that a treatment strategy combining intensive immunosuppression (using glucocorticoids and an IL-6 inhibitor) as well as close monitoring dramatically improves

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PIER MARIA FORNASARI
2020-07-22

Six symptom clusters in Covid19: A potential clinical prediction tool from the COVID Symptom study app

An analysis of data obtained from a symptom tracker app has shown that there are six distinct “types” of covid-19, each distinguished by a cluster of symptoms. The researchers said that these types could be used to predict the need for respiratory support in severe covid-19. The study is available online as a preprint and

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PIER MARIA FORNASARI
2020-07-22

CDC says COVID-19 cases may be 6 to 24 times higher than reported in some areas

In some parts of the U.S., COVID-19 cases may be six to 24 times higher than reported figures, according to new antibody data from the CDC. The data covers more than 16,000 blood samples collected from patients as part of routine care in 10 cities and states between March 23 and May 12. The CDC shared preliminary antibody data

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PIER MARIA FORNASARI
2020-07-21

Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19

A recent article suggested the rapid decay of anti–SARS-CoV-2 IgG in early infection, but the rate was not described in detail. In this correspondence just published on The New England Journal a total of 31 of the 34 participants had two serial measurements of IgG levels and the remaining 3 participants had three serial measurements.

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PIER MARIA FORNASARI
2020-07-21

International Society Thrombosis and Hemostasis Experts Explain New Blood Clotting Phenomenon in Hospitalized COVID-19 Patients

As the world continues to learn more about COVID-19, emerging data reveals that hospitalized patients with COVID-19 have an increased risk for blood clots. In a new Illustrated Review published in Research and Practice in Thrombosis and Haemostasis (RPTH) , leading thrombosis experts Prof. Beverley Hunt, OBE, and Prof. Marcel Levi, explain a clotting phenomenon found in most hospitalized

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PIER MARIA FORNASARI
2020-07-21

SARS-CoV-2 Nsp1 protein shuts down host protein production and subsequently blocks host immune functions.

A SARS-CoV-2 protein, N-terminal nonstructural protein 1 (Nsp1) , may play a critical role in weakening antiviral innate immune defenses, according to a study published in Science on July 17. Researchers identified how the viral protein specifically shuts down host protein production and subsequently blocks host immune functions. Following host infection, precursor proteins are proteolytically cleaved into

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PIER MARIA FORNASARI
2020-07-20

Korean study shows teenagers may transmit COVID-19 as much as adults do

Since the early days of the coronavirus pandemic, scientists and health authorities have often observed that children do not appear to contract and transmit the virus to the same extent as adults. While the mechanisms behind this reduced vulnerability have remained somewhat mysterious and speculative, new evidence from South Korea shows that the age of children is also a vital factor to

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PIER MARIA FORNASARI
2020-07-20

ICU mortality for Covid-19: a review shows a drop of one third in two months period

Overall mortality of covid-19 patients in intensive care units (ICU) has fallen from 59.5% at the end of March to 41.6% at the end of May, a drop of almost a third, researchers have said. The team from England carried out a systematic review and meta-analysis of published studies from Asia, Europe, and North America,

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PIER MARIA FORNASARI
2020-07-20

Covid-19 and convalescent plasma treatment potential: the NIH position

Recommendation There are insufficient data for the COVID-19 Treatment Guidelines Panel (the Panel) to recommend either for or against the use of COVID-19 convalescent plasma for the treatment of COVID-19. Rationale for Recommendation Thousands of patients in the United States have received COVID-19 convalescent plasma through clinical trials, expanded access treatment trials, and single-patient Emergency Investigational New

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PIER MARIA FORNASARI
2020-07-19

A synergistic role of convalescent plasma and mesenchymal stem cells in the treatment of severely ill COVID-19 patients: a clinical case report

Acute respiratory distress syndrome virus-2 (SARS-CoV-2) responsible for coronavirus disease 2019 (COVID-19) infection, which causes global public health emergencies, has sped widely for more than 5 months and has the risk of long-term transmission. No effective treatment has been discovered to date. In the cases reported, the patient continued to deteriorate even after administration of

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Archives: 2020-07-23

High-dose glucocorticoids and IL-6 receptor inhibition reduce COVID-19-associated cytokine storm mortality

Six symptom clusters in Covid19: A potential clinical prediction tool from the COVID Symptom study app

CDC says COVID-19 cases may be 6 to 24 times higher than reported in some areas

Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19

International Society Thrombosis and Hemostasis Experts Explain New Blood Clotting Phenomenon in Hospitalized COVID-19 Patients

SARS-CoV-2 Nsp1 protein shuts down host protein production and subsequently blocks host immune functions.

Korean study shows teenagers may transmit COVID-19 as much as adults do

ICU mortality for Covid-19: a review shows a drop of one third in two months period

Covid-19 and convalescent plasma treatment potential: the NIH position

A synergistic role of convalescent plasma and mesenchymal stem cells in the treatment of severely ill COVID-19 patients: a clinical case report