Archives: 2020-05-09

PIER MARIA FORNASARI
2020-05-09

Covid-19 Treatment with a Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin

Effective antiviral therapy is important for tackling the coronavirus disease 2019 (COVID-19) pandemic. In this paper published on The Lancet the efficacy and safety of combined interferon beta-1b, lopinavir–ritonavir, and ribavirin for treating patients with COVID-19 was assessed. Methods This was a multicentre, prospective, open-label, randomised, phase 2 trial in adults with COVID-19 who were

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PIER MARIA FORNASARI
2020-05-09

Can COVID-19 Cause Sepsis? Explaining the Relationship Between the Coronavirus Disease and Sepsis

The rapid global spread of the novel coronavirus SARS–CoV–2 has caused societal, economic, and medical upheaval not seen since the 1918 influenza pandemic. As of May 9th, cases were confirmed in 203 countries, areas or territories, with over 3.9 million confirmed cases and over 275,000 deaths.  Further, many experts believe these numbers to be a

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PIER MARIA FORNASARI
2020-05-08

Bioethicist condemn unproven and unlicensed ‘stem cell treatments’ for COVID-19

As the COVID-19 pandemic enters its third month, businesses in the United States are marketing unlicensed and unproven stem-cell-based “therapies” and exosome products that claim to prevent or treat the disease. In Cell Stem Cell on May 5, bioethicist Leigh Turner describes how these companies are “seizing the pandemic as an opportunity to profit from hope and

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PIER MARIA FORNASARI
2020-05-07

Researchers investigate how a potent mAb blocks SARS-CoV-2

Based on previous research that explored therapies against SARS-CoV, a new report has identified a fully human monoclonal antibody (mAb) that prevents the SARS-CoV-2 virus from infecting cultured cells. Authored by a team of researchers from Utrecht University, Erasmus Medical Center, and Harbour BioMed, the report was published in Nature Communications on May 4. Monoclonal antibodies that

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PIER MARIA FORNASARI
2020-05-06

Researchers in the US and UK have identified hundreds of mutations to Covid-19 coronavirus emerged in Europe in February.

Preliminary research from the US has suggested one particular mutation – G614 -has emerged in Europe and become dominant around the planet, leading the researchers to believe the virus has mutated to become more contagious. The paper hasn’t yet been reviewed by other scientists and formally published. The bold hypothesis, however, was immediately met with skepticism

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PIER MARIA FORNASARI
2020-05-06

Raised alarm on unproven stem cells marketing as COVID therapy

Scientists and international bodies including Stem Cells Australia, the International Society for Stem Cell Research, the International Society for Cell and Gene Therapy and EuroStemCell have raised the alarm about the marketing of unproven therapies during the pandemic, warning of damage to patients and to the credibility of the field. Source The Medical Republic Professor Daniel

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PIER MARIA FORNASARI
2020-05-06

FDA Recommendations for Investigational COVID-19 Convalescent Plasma

FDA has issued guidance to provide recommendations to health care providers and investigators on the administration and study of investigational convalescent plasma collected from individuals who have recovered from COVID-19 (COVID-19 convalescent plasma) during the public health emergency. The guidance provides recommendations on the following: pathways for use of investigational COVID-19 convalescent plasma patient eligibility collection of

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PIER MARIA FORNASARI
2020-05-06

Higher levels of destructive white blood cells associated with more severe COVID-19

Researchers believe the NETs may be relevant to numerous aspects of novel coronavirus as thrombosis and inflammation are hallmarks of the severe infection. Source: University of Michigan New research finds a connection between destructive white blood cells and a more severe disease course in patients with COVID-19. “We found that patients with COVID-19 infection have higher

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PIER MARIA FORNASARI
2020-05-06

COVID-19 Convalescent Plasma Transfusion: European Commission support a study

EU CCP Database – Covid-19 convalescent plasma collection and transfusion in the EU The European Commission is working together with Member States, the European Blood Alliance (EBA), the European Centre for Disease Prevention and Control (ECDC) and other health professionals to support a study of convalescent plasma as a treatment for COVID-19 patients. The study complements the guidance issued

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