Archives: 2020-04-10

PIER MARIA FORNASARI
2020-04-10

Pluristem sees positive signs in seven COVID-19 patients anedoctically treated with its allogeneic placental expanded (PLX) cells. International trial requested

Pluristem, an Israeli regenerative medicine company, associated with RESTORE community, said several of the seven COVID-19 patients treated with its allogeneic placental expanded (PLX) cells have progressed from suffering severe symptoms of the disease to signs of clinical recovery, including respiratory improvements. Encouraged by the experiment, carried out a under compassionate use program, the company

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PIER MARIA FORNASARI
2020-04-09

COVID-19 drug lead treatments identified

An international team of researchers has tested more than 10,000 compounds to identify six drug candidates that may help treat COVID-19. The research, involving University of Queensland scientist Professor Luke Guddat, tested the efficacy of approved drugs, drug candidates in clinical trials and other compounds. “Currently there are no targeted therapeutics or effective treatment options for

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PIER MARIA FORNASARI
2020-04-09

USC Researchers Analyze Covid-19 Misinformation on Twitter

By analyzing millions of tweets, USC computer science researchers are investigating how false information about the coronavirus spreads on social media. As concerns over the novel coronavirus have surged, so too has misinformation on social media—from false claims about hot water eliminating the virus to hoaxes about nationwide quarantines. In fact, posts, texts and email

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PIER MARIA FORNASARI
2020-04-08

About 30% of recovered patients generated very low titers of SARS-CoV-2 specific NAbs

Scientists in Shanghai say some recovered patients show no signs of the neutralising proteins Early-stage findings could have implications for vaccine development and herd immunity, they say Researchers in Shanghai hope to determine whether some recovered coronavirus patients have a higher risk of reinfection after finding surprisingly low levels of Covid-19 antibodies in a number of people

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PIER MARIA FORNASARI
2020-04-07

Analysis of Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

In a paper just published on JAMA is reported a retrospective case series that involved 1591 critically ill patients admitted from February 20 to March 18, 2020. 99% (1287 of 1300 patients) required respiratory support, including endotracheal intubation in 88% and noninvasive ventilation in 11%; ICU mortality was 26%. Retrospective case series were referred for

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PIER MARIA FORNASARI
2020-04-07

Chinese scientists seeking potential COVID-19 treatment find ‘effective’ antibodies in convalescent plasma

A team of Chinese scientists has isolated several antibodies that it says are “extremely effective” at blocking the ability of the new coronavirus to enter cells, which eventually could be helpful in treating or preventing COVID-19. There is currently no proven effective treatment for the disease, which originated in China and is spreading across the

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PIER MARIA FORNASARI
2020-04-07

ICNARC (intensive care national audit and research center) Report on 2249 patients critically ill with COVID-19

This report contains data on all confirmed COVID-19 cases reported to ICNARC up to midday on 03 April 2020 from critical care units participating in the Case Mix Programme (all NHS adult, general intensive care and combined intensive care/high dependency units inEngland, Wales and Northern Ireland, plus some specialist and non-NHS critical care units). Reporting

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PIER MARIA FORNASARI
2020-04-07

NICE advises against using NSAIDs for fever in patients with suspected cases of Covid-19

Paracetamol should be used in preference to non-steroidal anti-inflammatory drugs for managing fever in patients with suspected covid-19 until more evidence is available on the safety of NSAIDs, the National Institute for Health and Care Excellence advises in a rapid guideline on managing symptoms of covid-19 in the community.1 Patients with cough symptoms should take

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PIER MARIA FORNASARI
2020-04-06

FDA clears investigational new drug application for Mesoblast to use Remestemcel-L in patients with acute respiratory distress syndrome caused by COVID-19 under compassionate use and in a planned randomized controlled trial.

Mesoblast Limited today announced that it has received clearance from the United States Food and Drug Administration (FDA) for an Investigational New Drug (IND) application to treat patients with acute respiratory distress syndrome (ARDS) caused by coronavirus infection (COVID-19) with intravenous infusions of its allogeneic mesenchymal stem cell (MSC) product candidate Remestemcel-L. Mesoblast Chief Medical

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