The past 10 years witnessed a significant increase in the approval of cellular and gene therapy products worldwide. The US Food and Drug Administration (FDA) approved 3 gene therapy products within the last 4 months of 2017. The objective of this study was to examine the approval characteristics, discontinuations and cost of all cellular and
Researchers have infused cells edited using CRISPR-Cas9 into two patients in a trial conducted at the University of Pennsylvania, NPR reports today (April 16). A university spokesperson confirmed in an emailed statement to The Scientist that the trial is underway and that two patients, one with multiple myeloma and one with sarcoma, have been treated so far. The study is
Cardiovascular disease (CVD) remains the in the United States. And one of the most effective preventive measures to lower the risk of a CVD event are statins — a class of cholesterol-lowering medications. It’s well established that statins save lives, but a recent study finds that even after two years, half of all people prescribed statins don’t achieve healthy cholesterol levels.
More than half of U.S. adults take dietary supplements. I don’t, but some of my family members do. But does popping all of these vitamins, minerals, and other substances really lead to a longer, healthier life? A new nationwide study suggests it doesn’t. Based on an analysis of survey data gathered from more than 27,000
NIH research could be a step toward a treatment to prevent heart attacks Two proteins that bind to stress hormones work together to maintain a healthy heart in mice, according to scientists at the National Institutes of Health and their collaborators. These proteins, stress hormone receptors known as the glucocorticoid receptor (GR) and mineralocorticoid receptor
Hundreds of smartphone apps promise to make managing diabetes easier, but very few offer real-time guidance on what to do for dangerously high or low blood sugar, a US study suggests. Researchers looked at 5,185 apps for phones running Google’s Android software or Apple’s iOS system. Out of this total, they found 371 apps that claimed
Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from nonacademic institutions in February 2019. Business development Collaborations, partnerships & alliances Collaboration agreement: Pluristem & NASA Pluristem Therapeutics (Israel; www.pluristem.com) has collaborating with the NASA’s Ames Research Center to evaluate the potential of Pluristem’s PLX cell
Researchers discovered thousands of genes essential for cancer’s survival and ranked which ones show the most promise as drug targets for developing new treatments In one of the largest studies of its kind, researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key
Shooting electrical current into the brain for just 25 minutes reversed the decline in working memory that comes with aging, scientists reported on Monday. Although the researchers tested the effects on people for only 50 minutes, the finding offers hope for boosting a mental function that is so crucial for reasoning, everyday problem-solving, and planning
Diets that replaced red meat with healthy plant proteins led to decreases in risk factors for cardiovascular disease (CVD), according to a new study from Harvard T.H. Chan School of Public Health and Purdue University. The study is the first meta-analysis of randomized controlled trials examining the health effects of red meat by substituting it for
