Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have shown the feasibility of bioengineering vascularized functional renal tissues for kidney regeneration, developing a partial augmentation strategy that may be a more feasible and practical approach than creating whole organs. In the proof-of-concept study published online this month in Acta Biomaterialia journal, the scientists created a novel
A number of physiological and psychological changes occur as we age, and many studies have shown that our gut microbiome also changes as we grow older. A fascinating new study is suggesting that a shift in gut bacteria in our middle-age could trigger a process that plays a role in cognitive decline in our later years. And
York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation that could lead to new therapeutic targets to prevent the spread of muscle cancer. The researchers analyzed gene networks in muscle cells and found that the Smad7 and β-catenin proteins work co-operatively inside the
Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials. However, other than observing clinical outcomes, lack of a repeatable, time-sensitive and noninvasive tool to assess the effectiveness of the transplanted cells within the target organ has slowed progress in the stem cell field.
Johns Hopkins researchers have developed a way to map retinal cell development and potentially advance regenerative medicine Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells. The technique, demonstrated in mouse retinas for this study, follows the activity of
Source Future Medicine Mesenchymal stem cells (MSCs) are in development for many clinical indications, based both on ‘stem’ properties (tissue repair or regeneration) and on signaling repertoire (immunomodulatory and antiinflammatory effects). Potential conflation of MSC properties with those of tissue-derived stromal cells presents difficulties in comparing study outcomes and represents a source of confusion in
As discoveries around graphene applications abound, many are wondering if it can be scaled to 3D. This could have revolutionary effects, but it begs the question, have scientists been successful in graphene 3D printing? Find out! GRAPHENE 3D PRINTING Is It Possible? So, is it possible to 3D print graphene? The short answers is, not
US researchers from the University of Central Florida and Oregon Health and Science University have come together to review the history not only of prosthetics overall in the medical field but also to further inspect the transformation allowed by 3D printing. Contending that there are still many problems to be solved in prosthetics, the authors further explore children’s physical
The data-driven model sheds new light on mitosis, a critical process for human cells and a pivotal driver of cancer The Allen Institute today released the Integrated Mitotic Stem Cell, a data-driven model and visualization tool that captures — for the first time — a holistic view of human cell division. By enabling a deeper understanding
An international commission has been convened by the U.S. National Academy of Medicine (NAM), the U.S. National Academy of Sciences (NAS), and the Royal Society of the U.K., with the participation of science and medical academies around the world, to develop a framework for scientists, clinicians, and regulatory authorities to consider when assessing potential clinical
