Archives: 2019-07-22

Position Statement from the German Biobank Alliance on the Cooperation Between Academic Biobanks and Industry Partners

Under the umbrella of the German Biobank Node (GBN), 11 biobanks and two IT development centers are funded by the Federal Ministry of Education and Research (BMBF) to work together in the German Biobank Alliance (GBA). Their common aim is to make existing biomaterials hosted by different biobanks nationally and internationally available for biomedical research.

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The Landscape of Cellular and Gene Therapy Products: Authorization, Discontinuations, and Cost

Source Human Gene Therapy Clinical Development Background: Cell and gene therapy products belong to a diverse class of biopharmaceuticals known as advanced therapy medicinal products. Cell and gene therapy products are used for the treatment and prevention of diseases that until recently were only managed chronically. The objective of this study was to examine the characteristics

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Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

Researchers at the University of Calgary have discovered a previously unidentified cell population with the power to heal injured hearts. The cells were found in the pericardial fluid inside the sac around the heart.  Gata6+ pericardial cavity macrophage The study was led by Drs. Paul Kubes, PhD, Justin Deniset, PhD and Paul Fedak, MD, PhD. The specific

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Researchers at the National University of Singapore have developed artificial skin that almost works as well as the human one.

A team of scientists has managed to develop an electronic artificial skin that mimics that of humans. The new electronic skin can detect a range of tactile stimuli, such as temperature, pressure or object slippage in milliseconds without compromising accuracy or precision. It can also be used when partially damaged! The research team, from the National University

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The Mitochondrion as an Emerging Therapeutic Target in Cancer

Source https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(19)30171-6 Mitochondria display a dynamic and heterogeneous phenotype that facilitates the metabolic heterogeneity and plasticity of cancer cells. The altered metabolic functions and dynamics of mitochondria in cancer cells, as well as mitochondrial evasion of apoptosis, provide targets for novel cancer therapeutics. The mitochondrial network has distinct morphological features that appear to be interrelated

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ATMP Business and Clinical Updates

Source ARM Atara Biotherapeutics Announces Pricing of $150M Public OfferingJuly 18, 2019 – (Atara Biotherapeutics) – The offering is expected to close on or about July 23, 2019, subject to customary closing conditions. MilliporeSigma and Broad Institute Announce CRISPR License Framework to Encourage InnovationJuly 18, 2019 – (MilliporeSigma) – MilliporeSigma and the Broad Institute of MIT and Harvard

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Leading Innovation The UK’s ATMP Landscape New report

The Alliance for Regenerative Medicine (ARM) and UK BioIndustry Association (BIA) released a collaborative report offering an in-depth look at ATMP sector trends and metrics in the UK. The report details industry-specific statistics compiled from 56 cell therapy, gene therapy, tissue engineering, and other ATMP developers headquartered in the UK, including total financings, partnerships and other deals, clinical

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ILLUMINATING THE BRAIN WARREN ALPERT FOUNDATION AWARD GOES TO FOUR SCIENTISTS FOR SEMINAL DISCOVERIES IN OPTOGENETICS

Harnessing light and genetics, the approach illuminates and modulates the activity of neurons, enables study of brain function and behavior, sets stage for optogenetic therapies The 2019 Warren Alpert Foundation Prize has been awarded to four scientists for pioneering work in the field of optogenetics, a revolutionary technique that uses light and genetic modification to

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