SUTD leads in-depth review on the impending reality of 3D printed organs and analyses recent accomplishments, limitations and opportunities for future research. 3D bioprinting is a highly-advanced manufacturing platform that allows for the printing of tissue, and eventually vital organs, from cells. This could open a new world of possibilities for the medical field, while
Advance could help identify drugs to eventually treat fibrosis Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete. However, when healing is disrupted — whether by chronic
Shortly after updating the related draft Questions and Answers document, the European Commission has published two new documents concerning the Clinical Trials Regulation (EU) 536/2014. The first document is an informed consent and patient recruitment procedure template. The second document is an updated clinical trial Application Form. 2. Recruitment and Informed consent procedure template This draft template was developed
Organoids have extensive therapeutic potential and are increasingly opening up new avenues within regenerative medicine. Source Nature Communications Their clinical application is greatly limited by the lack of effective GMP-compliant systems for organoid expansion in culture. Here, it’s envisaged that the use of extracellular matrix (ECM) hydrogels derived from decellularized tissues (DT) can provide an
Findings from the ABC-PICU study may alter policies at hospitals where fresh red cells are preferentially used A new study led by the Sainte-Justine University Hospital Centre and the University of Montreal, and Washington University School of Medicine in St. Louis has found that transfusions using fresh red blood cells—cells that have spent seven days
Hematopoietic stem cells (HSCs) are responsible for the constant replenishment of all blood cells throughout life. One of the major challenges in regenerative medicine is to produce tailor-made HSCs to replace the defective ones in patients suffering from blood related diseases. This would circumvent the shortage of donor HSCs available for the clinic. To achieve
Led by researchers at Baylor College of Medicine, a study published in the journal Cell Stem Cell reveals a new mechanism that contributes to adult bone maintenance and repair and opens the possibility of developing therapeutic strategies for improving bone healing. “Adult bone repair relies on the activation of bone stem cells, which still remain poorly characterized,”
Scientists from The Australian National University (ANU) have invented a new jelly material that mimics biological matter such as skin, ligaments and bone, and which is very strong, self-healing and able to change shape. The team say the hydrogel could enable a new class of medical implants or artificial muscles for next-generation robots that could one
The International Society for Cell and Gene Therapy (ISCT) has formed a consortium to tackle what it says is a rising number of unscrupulous and unproven cell banking players. With the rise of interest in the cell and gene therapy sector, industry and the market have been plagued with unproven products and services from rogue
he world’s first integrated 3D bioprinter + confocal scanner (BioAssemblyBot + GE IN Cell Analyzer 6500HS) Strategic R&D and distribution partnership aims to advance the field of 3D biofabrication. Printed cells with vascularization would be first step toward more complex biological structures for bone, soft tissue, and organ replacements. The partners will create an integrated
