Source CancerNetwork CAR T cells are a more effective therapy if manufactured for patients with multiple myeloma prior to the onset of relapsed or refractory disease, according to study results1 published in Blood Advances. “CAR T cells directed against the B-cell maturation antigen (BCMA) have demonstrated impressive initial results, but available data suggest that most patients with initial responses
SMART has developed a new way to study cells, paving the way for a better understanding of how cancers spread and become deadly. Source Singapore-MIT Alliance for Research and Technology Researchers at Singapore-MIT Alliance for Research and Technology (SMART) and MIT’s Laser Biomedical Research Center (LBRC) have developed a new way to study cells, paving
Source MedCity News Interim Phase I/II data for Zolgensma showed improvements in children aged 2 to less than 5 with spinal muscular atrophy. The therapy received FDA approval in May for infants younger than 2. A gene therapy approved for treating spinal muscular atrophy in infants has also shown improved efficacy in older children. Basel,
Source University of Miami Health System Neuroscientists have been struggling for years to understand why neurons in the brain and spinal cord have so much difficulty re-growing connections after injury caused by trauma or disease. An intercontinental collaboration between the University of Miami and Imperial College London neuroscientists and computer scientists provides new insight into
The peptide nucleic acid-based technique offers an alternative to CRISPR-Cas9 A research team from Carnegie Mellon University and Yale University will advance their innovative, synthetic nucleic acid-based gene editing technique under a new grant from the National Institutes of Health’s (NIH’s) Somatic Cell Genome Editing (SCGE) Program. “Our PNA technique offers a promising avenue for treating — and possibly curing —
Terumo BCT’s latest cell therapy technology, the Finia® Fill and Finish System, is a first-of-its-kind device developed to help bring reproducibility and control to cell therapy manufacturing to get therapies to more patients who need them. Finia is a fully automated, modular, functionally closed system that creates the final formulation of cell and gene therapies
Penn study shows delivering a “distant cousin” of a key protein prevented muscle damage without triggering an immune response in large animal models A gene therapy being developed at Penn Medicine to treat Duchenne muscular dystrophy (DMD) successfully and safely stopped the severe muscle deterioration associated with the rare, genetic disease in both small and large animal
Twenty million Americans suffer from peripheral nerve injuries, which can be caused by traumas such as combat wounds and motorcycle crashes as well as medical disorders including diabetes. These injuries can have a devastating impact on quality of life, resulting in loss of sensation, motor function and long-lasting nerve pain. The body is capable of
Novel immunotherapy extends therapy now used in fighting leukemia, Tel Aviv University researchers say There is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherapy is still the most widely used cancer treatment, but chemotherapy attacks all the rapidly dividing cells that it locates within
Source Innovation Origins, Lucette Mascini Towards the end of the European Innovation Days, acclaimed scientists advised the European Commission and politicians on what to look out for when funding research with money from the EU’s Horizon Fund (amount: about €100 billion). These grants for scientific research are distributed by the European Research Council from the EU. You don’t have
